Recombinant Mouse ADAMTS1 Protein, CF | R&D Systems 5867-AD-020 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse ADAMTS1 Protein, CF

catalog :

5867-AD-020

quantity :

20 ug

price :

514 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Cheung S, Sayeed M, Nakuluri K, Li L, Feldman B. MYH9 facilitates autoregulation of adipose tissue depot development. JCI Insight. 2021;6: pubmed publisher
Wong J, Krueger K, Costa M, Aggarwal A, Du H, McLaughlin T, et al. A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo. Sci Signal. 2016;9:ra103 pubmed
Hellbach N, Weise S, Vezzali R, Wahane S, Heidrich S, Roidl D, et al. Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. Hum Mol Genet. 2014;23:6177-90 pubmed publisher
Lee Y, Koch M, Karl D, Torres Collado A, Fernando N, Rothrock C, et al. Variable inhibition of thrombospondin 1 against liver and lung metastases through differential activation of metalloproteinase ADAMTS1. Cancer Res. 2010;70:948-56 pubmed publisher

product information

master code :

5867-AD

SKU :

5867-AD-020

product name :

Recombinant Mouse ADAMTS1 Protein, CF

unit size :

20 ug

description :

The Recombinant Mouse ADAMTS1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse ADAMTS1 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

ADAMTS1

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Sodium Acetate, CaCl2 and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

65-70 kDa, reducing conditions

theoretical molecular weight :

53 kDa

details of functionality :

Measured by its ability to cleave Recombinant Human Aggrecan G1-IGD-G2 Domains (Catalog # 1220-PG ). rmADAMTS1 achieves 50% substrate cleavage, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P97857

applications :

Enzyme Activity

source long :

Chinese Hamster Ovary cell line, CHO-derived mouse ADAMTS1 protein Phe254-Cys725, with a C-terminal 10-His tag

source short :

CHO

USD :

514 USD

alt names :

a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1, ADAM metallopeptidase with thrombospondin type 1 motif, 1, ADAM-TS 1, ADAM-TS1, ADAMTS-1, C3-C5, METH1, METH-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage