product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-17A/F Heterodimer (CHO-expressed), CF
catalog :
5837-IL-010
quantity :
10 ug
price :
436 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Schminke B, Trautmann S, Mai B, Miosge N, Blaschke S. Interleukin 17 inhibits progenitor cells in rheumatoid arthritis cartilage. Eur J Immunol. 2016;46:440-5 pubmed publisher
product information
master code :
5837-IL
SKU :
5837-IL-010
product name :
Recombinant Human IL-17A/F Heterodimer (CHO-expressed), CF
unit size :
10 ug
description :
The Recombinant Human IL-17A/F Heterodimer (CHO-expressed), CF from R&D Systems is derived from CHO. The Recombinant Human IL-17A/F Heterodimer (CHO-expressed), CF has been validated for the following applications: Bioactivity.
target :
IL-17A/F Heterodimer
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in HCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
20 16 kDa, reducing conditions
theoretical molecular weight :
15.1 kDa (IL-17A) 14.9 kDa (IL-17F)
details of functionality :
Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.4-2 ng/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q16552 (IL-17A) Q96PD4 (IL-17F)
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived human IL-17A/F Heterodimer protein Human IL-17A (Gly24-Ala155) Accession # Q16552 Human IL-17F (Arg31-Gln163) Accession # Q96PD4 N-terminus C-terminus
source short :
CHO
USD :
436 USD
alt names :
CTLA8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, Cytotoxic T-Lymphocyte-Associated Protein 8, IL17, IL-17, IL-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A, interleukin-17A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.