Recombinant Human Follistatin 288 (FS-288) Protein | R&D Systems 5836-FS-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Follistatin 288 (FS-288) Protein

catalog :

5836-FS-025

quantity :

25 ug

price :

400 USD

more info or order :

R&D Systems product webpage

citations: 10

Reference
Baccouche B, Lietuvninkas L, Kazlauskas A. Activin A Limits VEGF-Induced Permeability via VE-PTP. Int J Mol Sci. 2023;24: pubmed publisher
Li J, Qi Y, Yang K, Zhu L, Cui X, Liu Z. Follistatin Is a Novel Chemoattractant for Migration and Invasion of Placental Trophoblasts of Mice. Cells. 2022;11: pubmed publisher
Mancinelli G, Torres C, Krett N, Bauer J, Castellanos K, McKinney R, et al. Role of stromal activin A in human pancreatic cancer and metastasis in mice. Sci Rep. 2021;11:7986 pubmed publisher
Bauer J, Emon M, Staudacher J, Thomas A, Zessner Spitzenberg J, Mancinelli G, et al. Increased stiffness of the tumor microenvironment in colon cancer stimulates cancer associated fibroblast-mediated prometastatic activin A signaling. Sci Rep. 2020;10:50 pubmed publisher
Staudacher J, Yazici C, Carroll T, Bauer J, Pang J, Krett N, et al. Activin in acute pancreatitis: Potential risk-stratifying marker and novel therapeutic target. Sci Rep. 2017;7:12786 pubmed publisher
Staudacher J, Bauer J, Jana A, Tian J, Carroll T, Mancinelli G, et al. Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer. Sci Rep. 2017;7:5569 pubmed publisher
Walker R, Czepnik M, Goebel E, McCoy J, Vujic A, Cho M, et al. Structural basis for potency differences between GDF8 and GDF11. BMC Biol. 2017;15:19 pubmed publisher
Choudhury Y, Toh Y, Xing J, Qu Y, Poh J, Li H, et al. Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity. Sci Rep. 2017;7:41238 pubmed publisher
Leddy H, McNulty A, Lee S, Rothfusz N, Gloss B, Kirby M, et al. Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations. FASEB J. 2014;28:2525-37 pubmed publisher
Mukhopadhyay A, Chan S, Lim I, Phillips D, Phan T. The role of the activin system in keloid pathogenesis. Am J Physiol Cell Physiol. 2007;292:C1331-8 pubmed

product information

brand :

R&D Systems

master code :

5836-FS

SKU :

5836-FS-025

product name :

Recombinant Human Follistatin 288 (FS-288) Protein

unit size :

25 ug

seo description :

The Recombinant Human Follistatin 288 (FS-288) Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human Follistatin 288 (FS-288) Protein has been validated for the following applications: Bioactivity.

target :

Follistatin

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

35-40 kDa, reducing conditions

theoretical molecular weight :

31.7 kDa

gene symbol :

FST

details of functionality :

Measured by its ability to neutralize Activin-mediated erythroid differentiation of K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 0.05-0.25 ╡g/mL in the presence of 7.5 ng/mL of rhActivin A.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P19883

applications :

Bioactivity

source :

Sf 21 (baculovirus)-derived Recombinant Human Follistatin 288 (FS-288) Protein

USD :

400 USD

alt names :

follistatin, follistatin isoform FST317, FS, FSActivin-binding protein, FST

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage