product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat TIMP-1 Protein, CF
catalog :
580-RT-010
quantity :
10 ug
price :
516 USD
more info or order :
R&D Systems product webpage
citations: 5
Reference
Sanz R, Ferraro G, Girouard M, Fournier A. Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons. Sci Rep. 2017;7:7961 pubmed publisher
Fjære E, Andersen C, Myrmel L, Petersen R, Hansen J, Tastesen H, et al. Tissue Inhibitor Of Matrix Metalloproteinase-1 Is Required for High-Fat Diet-Induced Glucose Intolerance and Hepatic Steatosis in Mice. PLoS ONE. 2015;10:e0132910 pubmed publisher
Ramezani Moghadam M, Wang J, Ho V, Iseli T, Alzahrani B, Xu A, et al. Adiponectin reduces hepatic stellate cell migration by promoting tissue inhibitor of metalloproteinase-1 (TIMP-1) secretion. J Biol Chem. 2015;290:5533-42 pubmed publisher
Sanz R, Ferraro G, Fournier A. IgLON cell adhesion molecules are shed from the cell surface of cortical neurons to promote neuronal growth. J Biol Chem. 2015;290:4330-42 pubmed publisher
Birukawa N, Murase K, Sato Y, Kosaka A, Yoneda A, Nishita H, et al. Activated hepatic stellate cells are dependent on self-collagen, cleaved by membrane type 1 matrix metalloproteinase for their growth. J Biol Chem. 2014;289:20209-21 pubmed publisher
product information
brand :
R&D Systems
master code :
580-RT
SKU :
580-RT-010
product name :
Recombinant Rat TIMP-1 Protein, CF
unit size :
10 ug
seo description :
The Recombinant Rat TIMP-1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat TIMP-1 Protein, CF has been validated for the following applications: Inhibition Activity.
target :
TIMP-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Tris and NaCl.
conjugate :
Unconjugated
dilution :
Inhibition Activity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
observed molecular weight :
32-34 kDa, reducing conditions
theoretical molecular weight :
21.5 kDa
gene symbol :
Timp1
details of functionality :
Measured by its ability to inhibit human MMP-2 cleavage of a fluorogenic peptide substrate Mca-PLGL-Dpa-AR-NH2 (Catalog # ES001 ). The IC50 value is 3.0 nM, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P30120
applications :
Inhibition Activity
source :
NS0-derived Recombinant Rat TIMP-1 Protein, CF
USD :
516 USD
alt names :
CLGI, Collagenase inhibitor, collagenase inhibitor), EPATIMP-1, EPO, erythroid potentiating activity, Erythroid-potentiating activity, Fibroblast collagenase inhibitor, FLJ90373, HCI, metalloproteinase inhibitor 1, TIMP metallopeptidase inhibitor 1, TIMP1, TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, Tissue inhibitor of metalloproteinases 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.