Recombinant Mouse IGFBP-5 Protein, CF | R&D Systems 578-B5-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IGFBP-5 Protein, CF

catalog :

578-B5-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Su Y, Cao Y, Liu C, Xu Q, Li N, Lan M, et al. Inactivating IL34 promotes regenerating muscle stem cell expansion and attenuates Duchenne muscular dystrophy in mouse models. Theranostics. 2023;13:2588-2604 pubmed publisher
Dong R, Bai Y, Dai J, Deng M, Zhao C, Tian Z, et al. Engineered scaffolds based on mesenchymal stem cells/preosteoclasts extracellular matrix promote bone regeneration. J Tissue Eng. 2020;11:2041731420926918 pubmed publisher
Lui J, Garrison P, Nguyen Q, Ad M, Keembiyehetty C, Chen W, et al. EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy. Nat Commun. 2016;7:13685 pubmed publisher

product information

master code :

578-B5

SKU :

578-B5-025

product name :

Recombinant Mouse IGFBP-5 Protein, CF

unit size :

25 ug

description :

The Recombinant Mouse IGFBP-5 Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse IGFBP-5 Protein, CF has been validated for the following applications: Bioactivity.

target :

IGFBP-5

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

28-38 kDa triplet, reducing conditions

theoretical molecular weight :

28.9 kDa

gene symbol :

Igfbp5

details of functionality :

Measured by its ability to inhibit the biological activity of IGF-I or IGF-II on MCF-7 human breast cancer cells. Karey, K.P. et al . (1988) Cancer Research 48 :4083. The ED50 for this effect is 0.5-2.5á╡g/mL in the presence of 30áng/mL of rmIGF-II.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q3UQV0

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse IGFBP-5 protein Val15-Glu271

source short :

NS0

USD :

432 USD

alt names :

IBP5IBP-5, IGF-binding protein 5, IGFBP5, IGFBP-5, insulin-like growth factor binding protein 5, insulin-like growth factor-binding protein 5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage