Recombinant Mouse L-Selectin/CD62L Fc Chimera Protein, CF | R&D Systems 576-LS-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse L-Selectin/CD62L Fc Chimera Protein, CF

catalog :

576-LS-100

quantity :

100 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Lien T, Sun D, Chang H. Targeted Delivery to Dying Cells Through P-Selectin-PSGL-1 Axis: A Promising Strategy for Enhanced Drug Efficacy in Liver Injury Models. Cells. 2024;13: pubmed publisher
Zuchtriegel G, Uhl B, Puhr Westerheide D, PÃ¶rnbacher M, Lauber K, Krombach F, et al. Platelets Guide Leukocytes to Their Sites of Extravasation. PLoS Biol. 2016;14:e1002459 pubmed publisher
Krishnamurthy V, Sardar M, Ying Y, Song X, Haller C, Dai E, et al. Glycopeptide analogues of PSGL-1 inhibit P-selectin in vitro and in vivo. Nat Commun. 2015;6:6387 pubmed publisher
Shigeta A, Matsumoto M, Tedder T, Lowe J, Miyasaka M, Hirata T. An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation. Blood. 2008;112:4915-23 pubmed publisher
Yamanaka K, Dimitroff C, Fuhlbrigge R, Kakeda M, Kurokawa I, Mizutani H, et al. Vitamins A and D are potent inhibitors of cutaneous lymphocyte-associated antigen expression. J Allergy Clin Immunol. 2008;121:148-157.e3 pubmed

product information

brand :

R&D Systems

master code :

576-LS

SKU :

576-LS-100

product name :

Recombinant Mouse L-Selectin/CD62L Fc Chimera Protein, CF

unit size :

100 ug

seo description :

The Recombinant Mouse L-Selectin/CD62L Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse L-Selectin/CD62L Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

L-Selectin/CD62L

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

150 kDa, reducing conditions

theoretical molecular weight :

60.5 kDa (monomer)

gene symbol :

Sell

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of LS180 human colorectal adenocarcinoma cells. When 5 x 104 cells/well are added to Recombinant Mouse L-Selectin/CD62L Fc Chimera coated plates, adhesion is induced in a dose dependent manner after a 1 hour incubation at 37 ░C. The ED50 for this effect is 0.3-1.2 ╡g/mL. . Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q3UV83

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse L-Selectin/CD62L Fc Chimera Protein, CF

USD :

456 USD

alt names :

CD62L, CD62L antigen, gp90-MEL, hLHRc, LAM1, LAM-1, LAM1LECAM1, LECAM1, Leu-8, LEU8, Leukocyte adhesion molecule 1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LNHR, LNHRTQ1, LSEL, L-selectin, Lyam-1, LYAM1, LYAM1CD62 antigen-like family member L, Lymph node homing receptor, lymphocyte adhesion molecule 1, pln homing receptor, PLNHR, selectin L, SELL, TQ1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage