Recombinant Human GDF-3 Protein | R&D Systems 5754-G3-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human GDF-3 Protein

catalog :

5754-G3-010

quantity :

10 ug

price :

400 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Zhao M, Okunishi K, Bu Y, Kikuchi O, Wang H, Kitamura T, et al. Targeting activin receptor-like kinase 7 ameliorates adiposity and associated metabolic disorders. JCI Insight. 2023;8: pubmed publisher
Kumar R, Grinberg A, Li H, Kuo T, Sako D, Krishnan L, et al. Functionally diverse heteromeric traps for ligands of the transforming growth factor-β superfamily. Sci Rep. 2021;11:18341 pubmed publisher
Jaeger P, Lucin K, Britschgi M, Vardarajan B, Huang R, Kirby E, et al. Network-driven plasma proteomics expose molecular changes in the Alzheimer's brain. Mol Neurodegener. 2016;11:31 pubmed publisher
Castonguay R, Werner E, Matthews R, Presman E, Mulivor A, Solban N, et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011;286:30034-46 pubmed publisher

product information

master code :

5754-G3

SKU :

5754-G3-010

product name :

Recombinant Human GDF-3 Protein

unit size :

10 ug

description :

The Recombinant Human GDF-3 Protein from R&D Systems is derived from CHO. The Recombinant Human GDF-3 Protein has been validated for the following applications: Bioactivity.

target :

GDF-3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in HCl with BSA as a carrier protein.

conjugate :

Unconjugated

species :

Human

observed molecular weight :

18 kDa, reducing conditions

theoretical molecular weight :

12.9 kDa

gene symbol :

GDF3

details of functionality :

Measured by its ability to induce Smad2 phosphorylation in P19 mouse embryonal carcinoma cells. Mazerbourg, S. et al . (2004) Mol. Endocrinol. 18 :653. 50 ng/mL of Recombinant Human GDF-3 can effectively induce Smad2 phosphorylation.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9NR23

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived human GDF-3 protein Ala251-Gly364

source short :

CHO

USD :

400 USD

alt names :

GDF3, GDF-3, growth differentiation factor 3, growth/differentiation factor 3, KFS3, MCOP7, MCOPCB6, Vgr-2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage