Recombinant Human CD35 Protein, CF | R&D Systems 5748-CD-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CD35 Protein, CF

catalog :

5748-CD-050

quantity :

50 ug

price :

567 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Chiu C, Tsai H, Chen J, Hu C, Chen H. An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity. Int J Nanomedicine. 2024;19:7201-7214 pubmed publisher
Lee S, Crosnier C, Valenzuela Leon P, Dizon B, Atkinson J, Mu J, et al. Complement receptor 1 is the human erythrocyte receptor for Plasmodium vivax erythrocyte binding protein. Proc Natl Acad Sci U S A. 2024;121:e2316304121 pubmed publisher
Prajapati S, Borlon C, Rovira Vallbona E, Gruszczyk J, Menant S, Tham W, et al. Complement Receptor 1 availability on red blood cell surface modulates Plasmodium vivax invasion of human reticulocytes. Sci Rep. 2019;9:8943 pubmed publisher
Zhao X, Larkin T, Lauver M, Ahmad S, Ducruet A. Tissue plasminogen activator mediates deleterious complement cascade activation in stroke. PLoS ONE. 2017;12:e0180822 pubmed publisher
Roy N, Ohtani K, Hidaka Y, Amano Y, Matsuda Y, Mori K, et al. Three pentraxins C-reactive protein, serum amyloid p component and pentraxin 3 mediate complement activation using Collectin CL-P1. Biochim Biophys Acta Gen Subj. 2017;1861:1-14 pubmed publisher
Chen Q, Wiesener M, Eberhardt H, Hartmann A, Uzonyi B, Kirschfink M, et al. Complement factor H-related hybrid protein deregulates complement in dense deposit disease. J Clin Invest. 2014;124:145-55 pubmed publisher

product information

brand :

R&D Systems

master code :

5748-CD

SKU :

5748-CD-050

product name :

Recombinant Human CD35 Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human CD35 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human CD35 Protein, CF has been validated for the following applications: Binding Activity.

target :

CD35

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Binding Activity

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

200-220 kDa, reducing conditions

theoretical molecular weight :

213 kDa

gene symbol :

CR1

details of functionality :

Measured by its binding ability in a functional ELISA. When rhCD35 is coated at 5 ╡g/mL, complement component C3b binds with an apparent KD 10 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

CAA68755

applications :

Binding Activity

source :

NS0-derived Recombinant Human CD35 Protein, CF

USD :

567 USD

alt names :

C3BR, CD35, complement component (3b/4b) receptor 1 (Knops blood group), CR1, KN

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage