Recombinant Human Integrin alpha 2 beta 1 Protein, CF | R&D Systems 5698-A2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha 2 beta 1 Protein, CF

catalog :

5698-A2

quantity :

50 ug

price :

389 USD

citations: 3

Reference
Long X, Wong C, Tong L, Chu E, Ho Szeto C, Go M, et al. Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity. Nat Microbiol. 2019;4:2319-2330 pubmed publisher
Kwon I, Hong S, Kim Y, Nam H, Kang S, Yang S, et al. Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice. PLoS ONE. 2013;8:e81165 pubmed publisher
Haidari M, Zhang W, Caivano A, Chen Z, Ganjehei L, Mortazavi A, et al. Integrin ?2?1 mediates tyrosine phosphorylation of vascular endothelial cadherin induced by invasive breast cancer cells. J Biol Chem. 2012;287:32981-92 pubmed

product information

brand :

R&D Systems

master code :

5698-A2

SKU :

5698-A2-050

product name :

Recombinant Human Integrin alpha 2 beta 1 Protein, CF

description :

The Recombinant Human Integrin alpha 2 beta 1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha 2 beta 1 Protein, CF has been validated for the following applications: Binding Activity.

target :

Integrin alpha 2 beta 1

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

140-150 kDa ( alpha 2) 120-130 kDa ( beta 1), reducing conditions

theoretical molecular weight :

126 kDa ( alpha 2) 83.3 kDa ( beta 1)

gene symbol :

ITGA2

details of functionality :

Measured by its binding ability in a functional ELISA. When bovine collagen-II is coated at 10 µg/mL, Recombinant Human Integrin alpha 2 beta 1 binds with an apparent Kd 1nM.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

5698-A2

accessionNumbers :

NP_002194 (Integrin alpha 2) P05556 (Integrin beta 1)

applications :

Binding Activity

source :

Chinese Hamster Ovary cell line, CHO-derived human Integrin alpha 2 beta 1 protein Human Integrin alpha 2 (Tyr30-Thr1132) Accession # NP_002194 HPGGGSGGGS Human c-Jun (Arg276-His315) Human Integrin beta 1 (Gln21-Asp728) Accession # P05556 GGGSGGGS Human c-Fos (Leu161-Ala199) N-terminus C-terminus

2020 USD :

389

2021 USD :

389 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.