Recombinant Human Integrin alpha 2 beta 1 Protein, CF | R&D Systems 5698-A2-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Integrin alpha 2 beta 1 Protein, CF

catalog :

5698-A2-050

quantity :

50 ug

price :

491 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Zeltz C, Khalil M, Navab R, Tsao M. Collagen Type XI Inhibits Lung Cancer-Associated Fibroblast Functions and Restrains the Integrin Binding Site Availability on Collagen Type I Matrix. Int J Mol Sci. 2022;23: pubmed publisher
Long X, Wong C, Tong L, Chu E, Ho Szeto C, Go M, et al. Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity. Nat Microbiol. 2019;4:2319-2330 pubmed publisher
Kwon I, Hong S, Kim Y, Nam H, Kang S, Yang S, et al. Thrombolytic effects of the snake venom disintegrin saxatilin determined by novel assessment methods: a FeCl3-induced thrombosis model in mice. PLoS ONE. 2013;8:e81165 pubmed publisher
Haidari M, Zhang W, Caivano A, Chen Z, Ganjehei L, Mortazavi A, et al. Integrin ?2?1 mediates tyrosine phosphorylation of vascular endothelial cadherin induced by invasive breast cancer cells. J Biol Chem. 2012;287:32981-92 pubmed

product information

brand :

R&D Systems

master code :

5698-A2

SKU :

5698-A2-050

product name :

Recombinant Human Integrin alpha 2 beta 1 Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human Integrin alpha 2 beta 1 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human Integrin alpha 2 beta 1 Protein, CF has been validated for the following applications: Binding Activity.

target :

Integrin alpha 2 beta 1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Binding Activity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

140-150 kDa ( alpha 2) 120-130 kDa (▀1), reducing conditions

theoretical molecular weight :

126 kDa ( alpha 2) 83.3 kDa (▀1)

gene symbol :

ITGA2

details of functionality :

Measured by its binding ability in a functional ELISA. When bovine collagen-II is coated at 10 ╡g/mL, Recombinant Human Integrin alpha 2▀1 binds with an apparent Kd 1nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_002194 (Integrin alpha 2) P05556 (Integrin ▀1)

applications :

Binding Activity

source :

CHO-derived Recombinant Human Integrin alpha 2 beta 1 Protein, CF

USD :

491 USD

alt names :

alpha 2 integrin, alpha 2 subunit of VLA-2 receptor, BR, CD49 antigen-like family member B, CD49b, collagen receptor, glycoprotein Ia, GPIa, HPA-5, human platelet alloantigen 5, human platelet alloantigen system 5, integrin alpha-2, integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), platelet antigen Br, platelet glycoprotein GPIa, platelet membrane glycoprotein Ia, very late activation protein 2 receptor, alpha-2 subunit, very late activation receptor alpha-2 subunit, very late activation receptor subunit alpha-2, VLA-2, VLAA2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage