product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse L1CAM Fc Chimera Protein, CF
catalog :
5674-NC-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Nagaraj V, Mikhail M, Baronio M, Gatto A, Nayak A, Theis T, et al. Antagonistic L1 Adhesion Molecule Mimetic Compounds Inhibit Glioblastoma Cell Migration In Vitro. Biomolecules. 2022;12: pubmed publisher
Wiertz R, Marani E, Rutten W. Neural cell-cell and cell-substrate adhesion through N-cadherin, N-CAM and L1. J Neural Eng. 2011;8:046004 pubmed publisher
product information
master code :
5674-NC
SKU :
5674-NC-050
product name :
Recombinant Mouse L1CAM Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse L1CAM Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse L1CAM Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
L1CAM
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in MES and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
180-200 kDa, reducing conditions
theoretical molecular weight :
150.5 kDa (monomer)
gene symbol :
L1cam
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of Neuro-2A mouse neuroblastoma cells. Recombinant Mouse L1CAM Fc Chimera immobilized at 2.5 ╡g/mL with 100 ╡L/well will induce 40% cell adhesion. Optimal dilutions should be determined by each laboratory for each application.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P11627
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse L1CAM protein Mouse L1CAM (Met1-Glu1123) with a Phe176Leu Substitution Accession # P11627 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
source short :
NS0
USD :
432 USD
alt names :
antigen identified by monoclonal R1, CAML1, CAML1N-CAML1, CD171, CD171 antigen, HSAS, HSAS1, L1 cell adhesion molecule, MASA, MIC5, N-CAM-L1, NCAM-L1, neural cell adhesion molecule L1, S10, SPG1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.