product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse BMP-7 Protein
catalog :
5666-BP-010
quantity :
10 ug
price :
529 USD
more info or order :
R&D Systems product webpage
citations: 23
Reference
Toba K, Yamada A, Sasa K, Shirota T, Kamijo R. Expression of Kielin/chordin-like protein is regulated by BMP-2 in osteoblasts. Bone Rep. 2024;22:101793 pubmed publisher
O Sullivan J, Blacker T, Scott C, Chang W, Ahmed M, Yianni V, et al. Gradients of glucose metabolism regulate morphogen signalling required for specifying tonotopic organisation in the chicken cochlea. elife. 2023;12: pubmed publisher
Moulis M, Runser S, Glorieux L, Dauguet N, Vanderaa C, Gatto L, et al. Identification and implication of tissue-enriched ligands in epithelial-endothelial crosstalk during pancreas development. Sci Rep. 2022;12:12498 pubmed publisher
Yamamoto T, Diao Z, Murakami M, Shimokawa F, Matsui T, Funaba M. Factors affecting the induction of uncoupling protein 1 in C2C12 myogenic cells. Cytokine. 2022;157:155936 pubmed publisher
Habeeb N, Najafi S, PERRON J. Assessment of BMP responses in an in vitro model of acute ethanol toxicity. MethodsX. 2022;9:101631 pubmed publisher
Hu X, Wang H, Tian G, Hou C, Xu B, Zhao X, et al. Offspring production of haploid spermatid-like cells derived from mouse female germline stem cells with chromatin condensation. Cell Biosci. 2022;12:5 pubmed publisher
Cortez M, Masrorpour F, Ivan C, Zhang J, Younes A, Lu Y, et al. Bone morphogenetic protein 7 promotes resistance to immunotherapy. Nat Commun. 2020;11:4840 pubmed publisher
Wu R, Sedlmeier G, Kyjacova L, Schmaus A, Philipp J, Thiele W, et al. Hyaluronic acid-CD44 interactions promote BMP4/7-dependent Id1/3 expression in melanoma cells. Sci Rep. 2018;8:14913 pubmed publisher
Jovanovic V, Salti A, Tilleman H, Zega K, Jukic M, Zou H, et al. BMP/SMAD Pathway Promotes Neurogenesis of Midbrain Dopaminergic Neurons In Vivo and in Human Induced Pluripotent and Neural Stem Cells. J Neurosci. 2018;38:1662-1676 pubmed publisher
Jin Y, Cheng X, Lu J, Li X. Exogenous BMP-7 Facilitates the Recovery of Cardiac Function after Acute Myocardial Infarction through Counteracting TGF-?1 Signaling Pathway. Tohoku J Exp Med. 2018;244:1-6 pubmed publisher
Chen Y, Xu H, Lin G. Generation of iPSC-derived limb progenitor-like cells for stimulating phalange regeneration in the adult mouse. Cell Discov. 2017;3:17046 pubmed publisher
Awazu M, Nagata M, Hida M. BMP7 dose-dependently stimulates proliferation and cadherin-11 expression via ERK and p38 in a murine metanephric mesenchymal cell line. Physiol Rep. 2017;5: pubmed publisher
Hou Y, Kitaguchi T, Kriszt R, Tseng Y, Raghunath M, Suzuki M. Ca2+-associated triphasic pH changes in mitochondria during brown adipocyte activation. Mol Metab. 2017;6:797-808 pubmed publisher
Dharmarajan S, Fisk D, Sorenson C, Sheibani N, Belecky Adams T. Microglia activation is essential for BMP7-mediated retinal reactive gliosis. J Neuroinflammation. 2017;14:76 pubmed publisher
Mata Miranda M, Vazquez Zapien G, Rojas Lopez M, Sánchez Monroy V, Pérez Ishiwara D, Delgado Macuil R. Morphological, molecular and FTIR spectroscopic analysis during the differentiation of kidney cells from pluripotent stem cells. Biol Res. 2017;50:14 pubmed publisher
Yorgan T, Peters S, Jeschke A, Benisch P, Jakob F, Amling M, et al. The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5. J Bone Miner Res. 2015;30:1175-83 pubmed publisher
Davies J, Hohenstein P, Chang C, Berry R. A self-avoidance mechanism in patterning of the urinary collecting duct tree. BMC Dev Biol. 2014;14:35 pubmed publisher
Kiso H, Takahashi K, Saito K, Togo Y, Tsukamoto H, Huang B, et al. Interactions between BMP-7 and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations. PLoS ONE. 2014;9:e96938 pubmed publisher
Heinonen A, Rahman M, Dogbevia G, Jakobi H, Wolfl S, Sprengel R, et al. Neuroprotection by rAAV-mediated gene transfer of bone morphogenic protein 7. BMC Neurosci. 2014;15:38 pubmed publisher
Mong J, Panman L, Alekseenko Z, Kee N, Stanton L, Ericson J, et al. Transcription factor-induced lineage programming of noradrenaline and motor neurons from embryonic stem cells. Stem Cells. 2014;32:609-22 pubmed publisher
Brown A, Muthukrishnan S, Guay J, Adams D, Schafer D, Fetting J, et al. Role for compartmentalization in nephron progenitor differentiation. Proc Natl Acad Sci U S A. 2013;110:4640-5 pubmed publisher
Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet. 2013;45:34-42 pubmed publisher
Tramullas M, Lantero A, Diaz A, Morchón N, Merino D, Villar A, et al. BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation. J Neurosci. 2010;30:1502-11 pubmed publisher
product information
brand :
R&D Systems
master code :
5666-BP
SKU :
5666-BP-010
product name :
Recombinant Mouse BMP-7 Protein
unit size :
10 ug
seo description :
The Recombinant Mouse BMP-7 Protein from R&D Systems is derived from CHO. The Recombinant Mouse BMP-7 Protein has been validated for the following applications: Bioactivity.
target :
BMP-7
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in HCl with BSA as a carrier protein.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
16-20 kDa under reducing conditions
theoretical molecular weight :
15.6 kDa (monomer)
gene symbol :
Bmp7
details of functionality :
Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 0.125-0.5 ╡g/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_031583
applications :
Bioactivity
source :
CHO-derived Recombinant Mouse BMP-7 Protein
USD :
529 USD
alt names :
BMP7, BMP-7, bone morphogenetic protein 7, Eptotermin alfa, OP-1, OP-1OP1, Osteogenic protein 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.