product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Neuroglycan C/CSPG5 Protein, CF
catalog :
5665-NG-050
quantity :
50 ug
price :
554 USD
more info or order :
citations: 1
Reference
Ng A, Logan A, Schmidt E, Robinson F. The CMT4B disease-causing phosphatases Mtmr2 and Mtmr13 localize to the Schwann cell cytoplasm and endomembrane compartments, where they depend upon each other to achieve wild-type levels of protein expression. Hum Mol Genet. 2013;22:1493-506 pubmed publisher
product information
master code :
5665-NG
SKU :
5665-NG-050
product name :
Recombinant Mouse Neuroglycan C/CSPG5 Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse Neuroglycan C/CSPG5 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse Neuroglycan C/CSPG5 Protein, CF has been validated for the following applications: Bioactivity.
target :
Neuroglycan C/CSPG5
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
85-105 kDa, reducing conditions
theoretical molecular weight :
42.1 kDa
gene symbol :
Cspg5
details of functionality :
Measured by its ability to inhibit Recombinant Human Midkine (Catalog # 258-MD ) induced neurite outgrowth in E16-E18 rat embryonic cortical neurons. When 5 x 104 neurons per well are added to a plate pre-incubated with serial dilutions of rmNeuroglycan-C and 1 ╡g/mL of rhMidkine, the neurite outgrowth promotion is significantly inhibited in a dose dependent manner with an effect at 0.6-1.2 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
AAH55736
applications :
Bioactivity
source long :
Chinese Hamster Ovary cell line, CHO-derived mouse Neuroglycan C/CSPG5 protein Val31-Gln420, with a C-terminal 6-His tag
source short :
CHO
USD :
554 USD
alt names :
CALEB, chondroitin sulfate proteoglycan 5, chondroitin sulfate proteoglycan 5 (neuroglycan C), CSPG5, MGC44034, Neuroglycan C, NGC, NGCAcidic leucine-rich EGF-like domain-containing brain protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.