product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat Neuropilin-1 Fc Chimera (NS0-expressed), CF
catalog :
566-NNS-025
quantity :
25 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Uniewicz K, Cross M, Fernig D. Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis. J Biol Chem. 2011;286:12-23 pubmed publisher
Narazaki M, Segarra M, Tosato G. Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A. Blood. 2008;111:4126-36 pubmed publisher
McLennan R, Kulesa P. In vivo analysis reveals a critical role for neuropilin-1 in cranial neural crest cell migration in chick. Dev Biol. 2007;301:227-39 pubmed
product information
master code :
566-NNS
SKU :
566-NNS-025
product name :
Recombinant Rat Neuropilin-1 Fc Chimera (NS0-expressed), CF
unit size :
25 ug
description :
The Recombinant Rat Neuropilin-1 Fc Chimera (NS0-expressed), CF from R&D Systems is derived from NS0. The Recombinant Rat Neuropilin-1 Fc Chimera (NS0-expressed), CF has been validated for the following applications: Binding Activity.
target :
Neuropilin-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in Citrate Phosphate and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
observed molecular weight :
130-150 kDa, reducing conditions
theoretical molecular weight :
119 kDa (monomer)
gene symbol :
Nrp1
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized rrNpn-1/Fc Chimera at 2 ╡g/mL (100 ╡L/well) can bind rhVEGF165 in the presence of 2 ╡g/mL of heparin with an apparent KD 1 nM.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q9QWJ9
applications :
Binding Activity
source long :
Mouse myeloma cell line, NS0-derived rat Neuropilin-1 protein Rat Neuropilin-1 (Phe22 - Ala810) Accession # Q9QWJ9 R Rat Neuropilin-1 (Ser829 - Asp854) Accession # Q9QWJ9 IEGRDMD Human IgG1 (Pro100 - Lys330) 6-His tag N-terminus C-terminus R D Systems rat Npn-1 may represent a previously unreported splice isoform of rat Npn-1.
source short :
NS0
USD :
432 USD
alt names :
BDCA4, BDCA-4, CD304, CD304 antigen, DKFZp686A03134, DKFZp781F1414, neuropilin 1, neuropilin-1, Neuropilin1, NP1, NRP, NRP1, transmembrane receptor, Vascular endothelial cell growth factor 165 receptor, VEGF165R
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.