Recombinant Human Neuroligin 2/NLGN2 Protein, CF | R&D Systems 5645-NL-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Neuroligin 2/NLGN2 Protein, CF

catalog :

5645-NL-050

quantity :

50 ug

price :

541 USD

citations: 3

Reference
Shiwaku H, Katayama S, Gao M, Kondo K, Nakano Y, Motokawa Y, et al. Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia. Brain Behav Immun. 2023;111:32-45 pubmed publisher
Camporesi E, Lashley T, Gobom J, Lantero Rodriguez J, Hansson O, Zetterberg H, et al. Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers. Acta Neuropathol Commun. 2021;9:19 pubmed publisher
Brito Moreira J, Lourenco M, Oliveira M, Ribeiro F, Ledo J, Diniz L, et al. Interaction of amyloid-Î² (AÎ²) oligomers with neurexin 2Î± and neuroligin 1 mediates synapse damage and memory loss in mice. J Biol Chem. 2017;292:7327-7337 pubmed publisher

product information

master code :

5645-NL

SKU :

5645-NL-050

product name :

Recombinant Human Neuroligin 2/NLGN2 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Neuroligin 2/NLGN2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Neuroligin 2/NLGN2 Protein, CF has been validated for the following applications: Bioactivity.

target :

Neuroligin 2/NLGN2

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

85-95 kDa, reducing conditions

theoretical molecular weight :

72 kDa

gene symbol :

NLGN2

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Neuroligin 2/NLGN2 is immobilized at 1.5 ╡g/mL, Recombinant Human Neurexin 1▀/NXRN1b Fc Chimera (Catalog # 5268-NX ) binds with an apparent Kd 10 nM.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

EAW90197

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Neuroligin 2/NLGN2 protein Gln15-Ser660, with a C-terminal 6-His tag

source short :

NS0

USD :

541 USD

alt names :

EC 3.1.1, EC 3.1.1.1, KIAA1366neuroligin-2, neuroligin 2, NLGN2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.