product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Neuroligin 2/NLGN2 Protein, CF
catalog :
5645-NL-050
quantity :
50 ug
price :
541 USD
more info or order :
citations: 3
Reference
Shiwaku H, Katayama S, Gao M, Kondo K, Nakano Y, Motokawa Y, et al. Analyzing schizophrenia-related phenotypes in mice caused by autoantibodies against NRXN1α in schizophrenia. Brain Behav Immun. 2023;111:32-45 pubmed publisher
Camporesi E, Lashley T, Gobom J, Lantero Rodriguez J, Hansson O, Zetterberg H, et al. Neuroligin-1 in brain and CSF of neurodegenerative disorders: investigation for synaptic biomarkers. Acta Neuropathol Commun. 2021;9:19 pubmed publisher
Brito Moreira J, Lourenco M, Oliveira M, Ribeiro F, Ledo J, Diniz L, et al. Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice. J Biol Chem. 2017;292:7327-7337 pubmed publisher
product information
brand :
R&D Systems
master code :
5645-NL
SKU :
5645-NL-050
product name :
Recombinant Human Neuroligin 2/NLGN2 Protein, CF
unit size :
50 ug
seo description :
The Recombinant Human Neuroligin 2/NLGN2 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Neuroligin 2/NLGN2 Protein, CF has been validated for the following applications: Bioactivity.
target :
Neuroligin 2/NLGN2
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
observed molecular weight :
85-95 kDa, reducing conditions
theoretical molecular weight :
72 kDa
gene symbol :
NLGN2
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human Neuroligin 2/NLGN2 is immobilized at 1.5 ╡g/mL, Recombinant Human Neurexin 1▀/NXRN1b Fc Chimera (Catalog # 5268-NX ) binds with an apparent Kd 10 nM.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
EAW90197
applications :
Bioactivity
source :
NS0-derived Recombinant Human Neuroligin 2/NLGN2 Protein, CF
USD :
541 USD
alt names :
EC 3.1.1, EC 3.1.1.1, KIAA1366neuroligin-2, neuroligin 2, NLGN2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.