Recombinant Rat VEGF 164 Protein | R&D Systems 564-RV-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat VEGF 164 Protein

catalog :

564-RV-010

quantity :

10 ug (also 50 ug)

price :

407 USD

more info or order :

R&D Systems product webpage

citations: 34

Reference
Capilla L xf3 pez J, Hern xe1 ndez R, Carrero Rojas G, Calvo P, Alvarez F, de la Cruz R, et al. VEGF, but Not BDNF, Prevents the Downregulation of KCC2 Induced by Axotomy in Extraocular Motoneurons. Int J Mol Sci. 2024;25: pubmed publisher
Wu Y, Sun J, Lin Q, Wang D, Hai J. Sustained release of vascular endothelial growth factor A and basic fibroblast growth factor from nanofiber membranes reduces oxygen/glucose deprivation-induced injury to neurovascular units. Neural Regen Res. 2024;19:887-894 pubmed publisher
Wang P, Deng Z, Li A, Li R, Huang W, Cui J, et al. β-Catenin promotes long-term survival and angiogenesis of peripheral blood mesenchymal stem cells via the Oct4 signaling pathway. Exp Mol Med. 2022;54:1434-1449 pubmed publisher
Kalkowski L, Golubczyk D, Kwiatkowska J, Domzalska M, Walczak P, Malysz Cymborska I. Local autoimmune encephalomyelitis model in a rat brain with precise control over lesion placement. PLoS ONE. 2022;17:e0262677 pubmed publisher
Wang D, Jin K, Zhao P, Lin Q, Kang K, Hai J. Neuroprotective Effects of VEGF-A Nanofiber Membrane and FAAH Inhibitor URB597 Against Oxygen-Glucose Deprivation-Induced Ischemic Neuronal Injury. Int J Nanomedicine. 2021;16:3661-3678 pubmed publisher
Froger N, Matonti F, Roubeix C, Forster V, Ivkovic I, Brunel N, et al. VEGF is an autocrine/paracrine neuroprotective factor for injured retinal ganglion neurons. Sci Rep. 2020;10:12409 pubmed publisher
Díaz Coránguez M, Lin C, Liebner S, Antonetti D. Norrin restores blood-retinal barrier properties after vascular endothelial growth factor-induced permeability. J Biol Chem. 2020;295:4647-4660 pubmed publisher
Chen J, Tu C, Tang X, Li H, Yan J, Ma Y, et al. The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect. Stem Cell Res Ther. 2019;10:379 pubmed publisher
Li J, Tang F, Li R, Chen Z, Lee S, Fu C, et al. Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo. J Nutr Biochem. 2020;77:108268 pubmed publisher
Mousavi S, Skjeldal F, Fønhus M, Haugen L, Eskild W, Berg T, et al. Receptor-Mediated Endocytosis of VEGF-A in Rat Liver Sinusoidal Endothelial Cells. Biomed Res Int. 2019;2019:5496197 pubmed publisher
López Bellido R, Puig S, Huang P, Tsai C, Turner H, Galko M, et al. Growth factor signaling regulates mechanical nociception in flies and vertebrates. J Neurosci. 2019;: pubmed publisher
Rodrigues G, Mason M, Christie L, Hansen C, Hernandez L, Burke J, et al. Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability. Invest Ophthalmol Vis Sci. 2018;59:5836-5846 pubmed publisher
Chang C, Li K, Jiang S, Li B, Cao L, Wang P. Downregulation of TRPC6 expression is a critical molecular event during FK506 treatment for overactive bladder. Cell Calcium. 2018;77:8-19 pubmed publisher
Li M, Cui Y, He W, Deng X, Wang Y, Cai M, et al. Effects of Triple-Mutated Hypoxia-Inducible Factor-1α on Angiogenesis and Cardiac Function Improvement in Rats with Myocardial Infarction. Cell Physiol Biochem. 2018;50:2329-2340 pubmed publisher
Vitacolonna M, Belharazem D, Hohenberger P, Roessner E. In-vivo quantification of the revascularization of a human acellular dermis seeded with EPCs and MSCs in co-culture with fibroblasts and pericytes in the dorsal chamber model in pre-irradiated tissue. Cell Tissue Bank. 2017;18:27-43 pubmed publisher
Yu S, Yao S, Wen Y, Wang Y, Wang H, Xu Q. Angiogenic microspheres promote neural regeneration and motor function recovery after spinal cord injury in rats. Sci Rep. 2016;6:33428 pubmed publisher
Hannan J, Matsui H, Sopko N, Liu X, Weyne E, Albersen M, et al. Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion. Sci Rep. 2016;6:29416 pubmed publisher
Hudson N, Powner M, Sarker M, Burgoyne T, Campbell M, Ockrim Z, et al. Differential apicobasal VEGF signaling at vascular blood-neural barriers. Dev Cell. 2014;30:541-52 pubmed publisher
Weinkopff T, Mackenzie C, Eversole R, Lammie P. Filarial excretory-secretory products induce human monocytes to produce lymphangiogenic mediators. PLoS Negl Trop Dis. 2014;8:e2893 pubmed publisher
Trichonas G, Manola A, Morizane Y, Thanos A, Koufomichali X, Papakostas T, et al. A novel nonradioactive method to evaluate vascular barrier breakdown and leakage. Invest Ophthalmol Vis Sci. 2010;51:1677-82 pubmed publisher
Hu J, Dong A, Fernandez Ruiz V, Shan J, Kawa M, Martinez Ansó E, et al. Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma. Cancer Res. 2009;69:6951-9 pubmed publisher
Irani Y, Brereton H, Tilton R, Coster D, Williams K. Production of scFv antibody fragments from a hybridoma with functional activity against human vascular endothelial growth factor. Hybridoma (Larchmt). 2009;28:205-9 pubmed publisher
Kempen D, Lu L, Heijink A, Hefferan T, Creemers L, Maran A, et al. Effect of local sequential VEGF and BMP-2 delivery on ectopic and orthotopic bone regeneration. Biomaterials. 2009;30:2816-25 pubmed publisher
Marko S, Damon D. VEGF promotes vascular sympathetic innervation. Am J Physiol Heart Circ Physiol. 2008;294:H2646-52 pubmed publisher
Rocha F, Sundback C, Krebs N, Leach J, Mooney D, Ashley S, et al. The effect of sustained delivery of vascular endothelial growth factor on angiogenesis in tissue-engineered intestine. Biomaterials. 2008;29:2884-90 pubmed publisher
Skondra D, Noda K, Almulki L, Tayyari F, Frimmel S, Nakazawa T, et al. Characterization of azurocidin as a permeability factor in the retina: involvement in VEGF-induced and early diabetic blood-retinal barrier breakdown. Invest Ophthalmol Vis Sci. 2008;49:726-31 pubmed publisher
Cho C, Parashurama N, Park E, Suganuma K, Nahmias Y, Park J, et al. Homogeneous differentiation of hepatocyte-like cells from embryonic stem cells: applications for the treatment of liver failure. FASEB J. 2008;22:898-909 pubmed
Kuiper E, Hughes J, Van Geest R, Vogels I, Goldschmeding R, Van Noorden C, et al. Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina. Invest Ophthalmol Vis Sci. 2007;48:4267-76 pubmed
Rhodes K, Raivich G, Fawcett J. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience. 2006;140:87-100 pubmed
Namisaki T, Yoshiji H, Kojima H, Yoshii J, Ikenaka Y, Noguchi R, et al. Salvage effect of the vascular endothelial growth factor on chemically induced acute severe liver injury in rats. J Hepatol. 2006;44:568-75 pubmed
Rota R, Riccioni T, Zaccarini M, Lamartina S, Gallo A, Fusco A, et al. Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer. J Gene Med. 2004;6:992-1002 pubmed
Lennernas B, Albertsson P, Damber J, Norrby K. Antiangiogenic effect of metronomic paclitaxel treatment in prostate cancer and non-tumor tissue in the same animals: a quantitative study. APMIS. 2004;112:201-9 pubmed
Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R. Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein. Int J Dev Biol. 2003;47:15-29 pubmed
Maynard S, Min J, Merchan J, Lim K, Li J, Mondal S, et al. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia. J Clin Invest. 2003;111:649-58 pubmed

product information

brand :

R&D Systems

master code :

564-RV

SKU :

564-RV-010

product name :

Recombinant Rat VEGF 164 Protein

unit size :

10 ug (also 50 ug)

seo description :

The Recombinant Rat VEGF 164 Protein from R&D Systems is derived from NS0. The Recombinant Rat VEGF 164 Protein has been validated for the following applications: Bioactivity.

target :

VEGF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Rat

observed molecular weight :

25 kDa, reducing conditions

theoretical molecular weight :

19.2 kDa (monomer)

gene symbol :

Vegfa

details of functionality :

Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. Conn, G. et al . (1990) Proc. Natl. Acad. Sci. USA 87 :1323. The ED50 for this effect is 0.75-3.75 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Rat VEGF 164 Protein Bioactivity

accessionNumbers :

AAL07526.1

applications :

Bioactivity

source :

NS0-derived Recombinant Rat VEGF 164 Protein

USD :

407 USD

alt names :

MVCD1, VAS, vascular endothelial growth factor A, Vascular permeability factor, Vasculotropin, VEGFA, VEGF-A, VEGFMGC70609, VPF, VPFvascular endothelial growth factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage