product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IL-1 RII Fc Chimera Protein, CF
catalog :
563-MR-100
quantity :
100 ug
price :
529 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Akashi Y, Nagasaki A, Okawa H, Matsumoto T, Kondo T, Yatani H, et al. Cyclic Pressure-Induced Cytokines from Gingival Fibroblasts Stimulate Osteoclast Activity: Clinical Implications for Alveolar Bone Loss in Denture Wearers. J Prosthodont Res. 2022;: pubmed publisher
O Connor J, Sherry C, Guest C, Freund G. Type 2 diabetes impairs insulin receptor substrate-2-mediated phosphatidylinositol 3-kinase activity in primary macrophages to induce a state of cytokine resistance to IL-4 in association with overexpression of suppressor of cytokine signaling-3. J Immunol. 2007;178:6886-93 pubmed
product information
brand :
R&D Systems
master code :
563-MR
SKU :
563-MR-100
product name :
Recombinant Mouse IL-1 RII Fc Chimera Protein, CF
unit size :
100 ug
seo description :
The Recombinant Mouse IL-1 RII Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse IL-1 RII Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-1 RII
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
70-80 kDa, reducing conditions
theoretical molecular weight :
64.7 kDa (monomer)
gene symbol :
Il1r2
details of functionality :
Measured by its ability to inhibit IL-1 alpha -dependent proliferation in D10.G4.1 mouse helper T cells. Symons, J.A. etáal . (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. etáal . (eds): IRL Press. 272. Approximately 3-30 ╡g/mL of IL-1 RII will inhibit 50% of the biological response due to 50 pg/mL of recombinant mouse IL-1 alpha .
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q4FK69
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Mouse IL-1 RII Fc Chimera Protein, CF
USD :
529 USD
alt names :
beta, CD121b, CD121b antigen, IL-1 R beta, IL1R2, IL1RBCD121 antigen-like family member B, IL-1R-beta, IL1RII, IL-1RII, IL-1RT2, IL-1RT-2, interleukin 1 receptor, type II, Interleukin-1 receptor beta, MGC47725
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.