product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Siglec-1 Fc Chimera Protein, CF
catalog :
5610-SL-050
quantity :
50 ug
price :
523 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Chen G, Brown N, Wu W, Khedri Z, Yu H, Chen X, et al. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. elife. 2014;3:e04066 pubmed publisher
Xiong Y, Yu J, Li C, Zhu L, Wu L, Zhong R. The role of Siglec-1 and SR-BI interaction in the phagocytosis of oxidized low density lipoprotein by macrophages. PLoS ONE. 2013;8:e58831 pubmed publisher
product information
brand :
R&D Systems
master code :
5610-SL
SKU :
5610-SL-050
product name :
Recombinant Mouse Siglec-1 Fc Chimera Protein, CF
unit size :
50 ug
seo description :
The Recombinant Mouse Siglec-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Siglec-1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Siglec-1/CD169
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
190-205 kDa under reducing conditions
theoretical molecular weight :
201.7 kDa (monomer)
gene symbol :
Siglec1
details of functionality :
Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Kelm, S. et al . (1994) Current Biology 4 :965. The ED50 for this effect is 0.6-3 ╡g/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
CAM18034
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Siglec-1 Fc Chimera Protein, CF
USD :
523 USD
alt names :
CD169, FLJ00051, sialic acid binding Ig-like lectin 1, sialoadhesin, sialoadhesin, Siglec1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.