Recombinant Mouse Siglec-1 Fc Chimera Protein, CF | R&D Systems 5610-SL-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Siglec-1 Fc Chimera Protein, CF

catalog :

5610-SL-050

quantity :

50 ug

price :

523 USD

citations: 2

Reference
Chen G, Brown N, Wu W, Khedri Z, Yu H, Chen X, et al. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1. elife. 2014;3:e04066 pubmed publisher
Xiong Y, Yu J, Li C, Zhu L, Wu L, Zhong R. The role of Siglec-1 and SR-BI interaction in the phagocytosis of oxidized low density lipoprotein by macrophages. PLoS ONE. 2013;8:e58831 pubmed publisher

product information

master code :

5610-SL

SKU :

5610-SL-050

product name :

Recombinant Mouse Siglec-1 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse Siglec-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Siglec-1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Siglec-1/CD169

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

190-205 kDa under reducing conditions

theoretical molecular weight :

201.7 kDa (monomer)

gene symbol :

Siglec1

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of human red blood cells. Kelm, S. et al . (1994) Current Biology 4 :965. The ED50 for this effect is 0.6-3 ╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

CAM18034

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse Siglec-1/CD169 protein Mouse Siglec-1 (Thr20 - Arg1639) Accession # CAM18034 IEGRMDP Mouse IgG2a (Glu98 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

523 USD

alt names :

CD169, FLJ00051, sialic acid binding Ig-like lectin 1, sialoadhesin, sialoadhesin, Siglec1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.