product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human CA125/MUC16 Protein, CF
catalog :
5609-MU-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 12
Reference
Szymanska B, Lukaszewski Z, Hermanowicz Szamatowicz K, Gorodkiewicz E. A Multiple-Array SPRi Biosensor as a Tool for Detection of Gynecological-Oncological Diseases. Biosensors (Basel). 2023;13: pubmed publisher
Molinos Albert L, Lorin V, Monceaux V, Orr S, Essat A, Dufloo J, et al. Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers. Nat Commun. 2022;13:1944 pubmed publisher
Shon D, Fernandez D, Riley N, Ferracane M, Bertozzi C. Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences. J Biol Chem. 2022;298:101917 pubmed publisher
Song J, Sokoll L, Chan D, Zhang Z. Validation of Serum Biomarkers That Complement CA19-9 in Detecting Early Pancreatic Cancer Using Electrochemiluminescent-Based Multiplex Immunoassays. Biomedicines. 2021;9: pubmed publisher
Wu P, Pai C, Lee M, Lee W. A Single-Substrate Biosensor with Spin-Coated Liquid Crystal Film for Simple, Sensitive and Label-Free Protein Detection. Biosensors (Basel). 2021;11: pubmed publisher
Shaban H, Lee M, Lee W. Label-Free Detection and Spectrometrically Quantitative Analysis of the Cancer Biomarker CA125 Based on Lyotropic Chromonic Liquid Crystal. Biosensors (Basel). 2021;11: pubmed publisher
Malsagova K, Pleshakova T, Galiullin R, Kozlov A, Shumov I, Popov V, et al. Highly Sensitive Detection of CA 125 Protein with the Use of an n-Type Nanowire Biosensor. Biosensors (Basel). 2020;10: pubmed publisher
Fierle J, Abram Saliba J, Brioschi M, deTiani M, Coukos G, Dunn S. Integrating SpyCatcher/SpyTag covalent fusion technology into phage display workflows for rapid antibody discovery. Sci Rep. 2019;9:12815 pubmed publisher
Malaker S, Pedram K, Ferracane M, Bensing B, Krishnan V, Pett C, et al. The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins. Proc Natl Acad Sci U S A. 2019;116:7278-7287 pubmed publisher
Liu J, Palakurthi S, Zeng Q, Zhou S, Ivanova E, Huang W, et al. Establishment of Patient-Derived Tumor Xenograft Models of Epithelial Ovarian Cancer for Preclinical Evaluation of Novel Therapeutics. Clin Cancer Res. 2017;23:1263-1273 pubmed publisher
Fischer N, Elson G, Magistrelli G, Dheilly E, Fouque N, Laurendon A, et al. Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG. Nat Commun. 2015;6:6113 pubmed publisher
Prassas I, Brinc D, Farkona S, Leung F, Dimitromanolakis A, Chrystoja C, et al. False biomarker discovery due to reactivity of a commercial ELISA for CUZD1 with cancer antigen CA125. Clin Chem. 2014;60:381-8 pubmed publisher
product information
brand :
R&D Systems
master code :
5609-MU
SKU :
5609-MU-050
product name :
Recombinant Human CA125/MUC16 Protein, CF
unit size :
50 ug
seo description :
The Recombinant Human CA125/MUC16 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human CA125/MUC16 Protein, CF has been validated for the following applications: Binding Activity.
target :
CA125/MUC16
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
dilution :
Binding Activity
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
153-169 kDa, reducing conditions
theoretical molecular weight :
110 kDa
gene symbol :
MUC16
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human CA125/MUC16 is coated at 1 ╡g/mL (100 ╡L/well), the concentration of Recombinant Human Galectin-3 (Catalog # 1154-GA ) that produces 50% of the optimal binding response is found to be approximately 0.35-1.4 ╡g/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_078966.2
applications :
Binding Activity
source :
CHO-derived Recombinant Human CA125/MUC16 Protein, CF
USD :
432 USD
alt names :
CA-125, CA125 ovarian cancer antigen, CA125MUC-16, FLJ14303, MUC16, mucin 16, cell surface associated, mucin-16, Ovarian cancer-related tumor marker CA125, Ovarian carcinoma antigen CA125
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.