Recombinant Human EphA6 Fc Chimera Protein, CF | R&D Systems 5606-A6-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human EphA6 Fc Chimera Protein, CF

catalog :

5606-A6-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
El Fakiri M, Regupathy A, Uhlmann L, Ayada N, Geis N, Domogalla L, et al. Development and preclinical characterization of a novel radiotheranostic EphA2-targeting bicyclic peptide. Theranostics. 2024;14:4701-4712 pubmed publisher
Cha J, Chan L, Wang Y, Chu Y, Wang C, Lee H, et al. Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer. J Biol Chem. 2022;298:101817 pubmed publisher

product information

master code :

5606-A6

SKU :

5606-A6-050

product name :

Recombinant Human EphA6 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human EphA6 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Human EphA6 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

EphA6

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

95-110 kDa under reducing conditions

theoretical molecular weight :

85.7 kDa (monomer)

gene symbol :

EPHA6

details of functionality :

Measured by its binding ability in a functional ELISA. When rhEphA6/Fc Chimera is immobilized at 2 ╡g/mL, 100 ╡L/well, it binds biotinylated rhEphrin-A3/Fc Chimera with a linear range of 0.31-20 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAI56734

applications :

Binding Activity

source long :

Chinese Hamster Ovary cell line, CHO-derived human EphA6 protein Human EphA6 (Trp23-Val550) Accession # AAI56734 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

CHO

USD :

432 USD

alt names :

DKFZp434C1418, EC 2.7.10, EC 2.7.10.1, Ehk2, EHK-2, EPA6, EPH homology kinase 2, EPH receptor A6, ephrin receptor EphA6, ephrin type-A receptor 6, FLJ35246, Hek12, PRO57066

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage