product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat CNTFR alpha Protein
catalog :
558-CR-050
quantity :
50 ug
price :
468 USD
more info or order :
R&D Systems product webpage
citations: 2
Reference
Bucher F, Walz J, Bühler A, Aguilar E, Lange C, Diaz Aguilar S, et al. CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2016;57:4017-26 pubmed publisher
Mizisin A, Vu Y, Shuff M, Calcutt N. Ciliary neurotrophic factor improves nerve conduction and ameliorates regeneration deficits in diabetic rats. Diabetes. 2004;53:1807-12 pubmed
product information
master code :
558-CR
SKU :
558-CR-050
product name :
Recombinant Rat CNTFR alpha Protein
unit size :
50 ug
description :
The Recombinant Rat CNTFR alpha Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Rat CNTFR alpha Protein has been validated for the following applications: Bioactivity.
target :
CNTFR alpha
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Rat
observed molecular weight :
52 kDa, reducing conditions
theoretical molecular weight :
39.1 kDa
gene symbol :
Cntfr
details of functionality :
Measured by its ability to enhance CNTF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.05-0.15 ╡g/mL in the presence of 1 ng/mL of recombinant rat CNTF.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q08406
applications :
Bioactivity
source long :
Spodoptera frugiperda , Sf 21 (baculovirus)-derived rat CNTF R alpha protein Ala19-Pro346 & Gln23-Pro346
source short :
Sf 21 (baculovirus)
USD :
468 USD
alt names :
Ciliary neurotrophic factor receptor subunit alpha;Cntfr, CNTF R alpha, CNTFR, CNTFRa
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.