Recombinant Mouse BMP-9 Protein, CF | R&D Systems 5566-BP-010/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse BMP-9 Protein, CF

catalog :

5566-BP-010/CF

quantity :

10 ug

price :

529 USD

citations: 14

Reference
Ahmed T, Flores P, Pan C, Ortiz H, Lee Y, Langlais P, et al. EPDR1 is a noncanonical effector of insulin-mediated angiogenesis regulated by an endothelial-specific TGF-β receptor complex. J Biol Chem. 2022;298:102297 pubmed publisher
Yamamoto T, Diao Z, Murakami M, Shimokawa F, Matsui T, Funaba M. Factors affecting the induction of uncoupling protein 1 in C2C12 myogenic cells. Cytokine. 2022;157:155936 pubmed publisher
Marvin D, You L, Bornes L, Van Dinther M, Peters N, Dang H, et al. Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells. Cancers (Basel). 2022;14: pubmed publisher
Chiara Perego M, Bellitto N, Maylem E, Caloni F, Spicer L. Effects of selected hormones and their combination on progesterone and estradiol production and proliferation of feline granulosa cells cultured in vitro. Theriogenology. 2021;168:1-12 pubmed publisher
Tao B, Kraehling J, Ghaffari S, Ramírez C, Lee S, Fowler J, et al. BMP-9 and LDL crosstalk regulates ALK-1 endocytosis and LDL transcytosis in endothelial cells. J Biol Chem. 2020;295:18179-18188 pubmed publisher
Gadomski S, Singh S, Singh S, Sarkar T, Klarmann K, Berenschot M, et al. Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration. Cell Rep. 2020;31:107572 pubmed publisher
Gaitantzi H, Karch J, Germann L, Cai C, Rausch V, Birgin E, et al. BMP-9 Modulates the Hepatic Responses to LPS. Cells. 2020;9: pubmed publisher
Kim Y, Choe S, Chae M, Hong S, Oh S. SMAD4 Deficiency Leads to Development of Arteriovenous Malformations in Neonatal and Adult Mice. J Am Heart Assoc. 2018;7:e009514 pubmed publisher
Ouarné M, Bouvard C, Boneva G, Mallet C, Ribeiro J, Desroches Castan A, et al. BMP9, but not BMP10, acts as a quiescence factor on tumor growth, vessel normalization and metastasis in a mouse model of breast cancer. J Exp Clin Cancer Res. 2018;37:209 pubmed publisher
Ruiz S, Zhao H, Chandakkar P, Chatterjee P, Papoin J, Blanc L, et al. A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10. Sci Rep. 2016;5:37366 pubmed publisher
Alaa El Din F, Patri S, Thoreau V, Rodríguez Ballesteros M, Hamade E, Bailly S, et al. Functional and splicing defect analysis of 23 ACVRL1 mutations in a cohort of patients affected by Hereditary Hemorrhagic Telangiectasia. PLoS ONE. 2015;10:e0132111 pubmed publisher
Azuma K, Shiba S, Hasegawa T, Ikeda K, Urano T, Horie Inoue K, et al. Osteoblast-Specific Î³-Glutamyl Carboxylase-Deficient Mice Display Enhanced Bone Formation With Aberrant Mineralization. J Bone Miner Res. 2015;30:1245-54 pubmed publisher
Zhu D, Mackenzie N, Shanahan C, Shroff R, Farquharson C, Macrae V. BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway. J Cell Mol Med. 2015;19:165-74 pubmed publisher
Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet. 2013;45:34-42 pubmed publisher

product information

master code :

5566-BP/CF

SKU :

5566-BP-010/CF

product name :

Recombinant Mouse BMP-9 Protein, CF

unit size :

10 ug

description :

The Recombinant Mouse BMP-9 Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse BMP-9 Protein, CF has been validated for the following applications: Bioactivity.

target :

BMP-9

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

13 kDa, reducing conditions

theoretical molecular weight :

12.1 kDa

gene symbol :

Gdf2

details of functionality :

Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al . (1999) Exp. Cell Res. 250 :351. The ED50 for this effect is 0.5-4 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAD56961

applications :

Bioactivity

source long :

Chinese Hamster Ovary cell line, CHO-derived mouse BMP-9 protein Ser319-Arg428

source short :

CHO

USD :

529 USD

alt names :

BMP9, BMP9BMP-9Bone morphogenetic protein 9, GDF2, GDF-2, growth differentiation factor 2, growth/differentiation factor 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.