Recombinant Rat beta-NGF Protein | R&D Systems 556-NG-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat beta-NGF Protein

catalog :

556-NG-100

quantity :

100 ug

price :

373 USD

citations: 27

Reference
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Li J, Duan W, Chai S, Luo Y, Ma Y, Yang N, et al. Wogonin, a Bioactive Ingredient from Huangqi Guizhi Formula, Alleviates Discogenic Low Back Pain via Suppressing the Overexpressed NGF in Intervertebral Discs. Mediators Inflamm. 2023;2023:4436587 pubmed publisher
Koga T, Tai A. Neurite Outgrowth-Promoting Compounds from Cockscomb Hydrolysate. Nutrients. 2022;14: pubmed publisher
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Lee J, Hsu Y, Chiu Y, Jou I, Chang M. Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats. J Neuroinflammation. 2020;17:156 pubmed publisher
Yi J, Shin S, Kim N, Bang O. Ameliorative effects of aqueous extract of Forsythiae suspensa fruits on oxaliplatin-induced neurotoxicity in vitro and in vivo. BMC Complement Altern Med. 2019;19:339 pubmed publisher
Singh I, Lacko C, Zhao Z, Schmidt C, Rinaldi C. Preparation and evaluation of microfluidic magnetic alginate microparticles for magnetically templated hydrogels. J Colloid Interface Sci. 2020;561:647-658 pubmed publisher
Yi J, Shin S, Kim N, Bang O. Neuroprotective Effects of an Aqueous Extract of Forsythia viridissima and Its Major Constituents on Oxaliplatin-Induced Peripheral Neuropathy. Molecules. 2019;24: pubmed publisher
Wu X, Du J, Song W, Cao M, Chen S, Xia R. Weak power frequency magnetic fields induce microtubule cytoskeleton reorganization depending on the epidermal growth factor receptor and the calcium related signaling. PLoS ONE. 2018;13:e0205569 pubmed publisher
Haywood A, Hathway G, Chapman V. Differential contributions of peripheral and central mechanisms to pain in a rodent model of osteoarthritis. Sci Rep. 2018;8:7122 pubmed publisher
Göttle P, Manousi A, Kremer D, Reiche L, Hartung H, Küry P. Teriflunomide promotes oligodendroglial differentiation and myelination. J Neuroinflammation. 2018;15:76 pubmed publisher
He J, Dong X, Li Z, Wang X, Fu Z, Shen N. Pterostilbene inhibits reactive oxygen species production and apoptosis in primary spinal cord neurons by activating autophagy via the mechanistic target of rapamycin signaling pathway. Mol Med Rep. 2018;17:4406-4414 pubmed publisher
Kays J, Zhang Y, Khorodova A, Strichartz G, Nicol G. Peripheral Synthesis of an Atypical Protein Kinase C Mediates the Enhancement of Excitability and the Development of Mechanical Hyperalgesia Produced by Nerve Growth Factor. Neuroscience. 2018;371:420-432 pubmed publisher
Nevin Z, Factor D, Karl R, Douvaras P, Laukka J, Windrem M, et al. Modeling the Mutational and Phenotypic Landscapes of Pelizaeus-Merzbacher Disease with Human iPSC-Derived Oligodendrocytes. Am J Hum Genet. 2017;100:617-634 pubmed publisher
Khodorova A, Nicol G, Strichartz G. The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor. Neuroscience. 2017;340:384-397 pubmed publisher
Bacallao K, Monje P. Requirement of cAMP signaling for Schwann cell differentiation restricts the onset of myelination. PLoS ONE. 2015;10:e0116948 pubmed publisher
Bahrini I, Song J, Diez D, Hanayama R. Neuronal exosomes facilitate synaptic pruning by up-regulating complement factors in microglia. Sci Rep. 2015;5:7989 pubmed publisher
GÃ¶ttle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, et al. Oligodendroglial maturation is dependent on intracellular protein shuttling. J Neurosci. 2015;35:906-19 pubmed publisher
Zeng W, Rong M, Hu X, Xiao W, Qi F, Huang J, et al. Incorporation of chitosan microspheres into collagen-chitosan scaffolds for the controlled release of nerve growth factor. PLoS ONE. 2014;9:e101300 pubmed publisher
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product information

master code :

556-NG

SKU :

556-NG-100

product name :

Recombinant Rat beta-NGF Protein

unit size :

100 ug

description :

The Recombinant Rat beta-NGF Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Rat beta-NGF Protein has been validated for the following applications: Bioactivity.

target :

beta-NGF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and NaCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

theoretical molecular weight :

13.2 kDa (monomer)

gene symbol :

Ngf

details of functionality :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.1-0.6 ng/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Rat beta-NGF Protein Bioactivity

accessionNumbers :

P25427.2

applications :

Bioactivity

source long :

Spodoptera frugiperda , Sf 21 (baculovirus)-derived rat beta-NGF protein Ser122-Gly241

source short :

Sf 21 (baculovirus)

USD :

373 USD

alt names :

Beta nerve growth factor precursor, beta-nerve growth factor, betaNGF, Beta-NGF, HSAN5, MGC161426, nerve growth factor (beta polypeptide), nerve growth factor, beta subunit, NGFB, NGFBMGC161428

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.