product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat IL-10 (Cys167Tyr) Protein, CF
catalog :
547-RL-010/CF
quantity :
10 ug
price :
355 USD
more info or order :
citations: 4
Reference
Malik A, Bagchi A, Jassal D, Singal P. Interleukin-10 Mitigates Doxorubicin-Induced Endoplasmic Reticulum Stress as Well as Cardiomyopathy. Biomedicines. 2022;10: pubmed publisher
Lim S, Park E, You B, Jung Y, Park A, Park S, et al. Neuronal synapse formation induced by microglia and interleukin 10. PLoS ONE. 2013;8:e81218 pubmed publisher
Hollis J, Lemus M, Evetts M, Oldfield B. Central interleukin-10 attenuates lipopolysaccharide-induced changes in food intake, energy expenditure and hypothalamic Fos expression. Neuropharmacology. 2010;58:730-8 pubmed publisher
Roche M, Diamond M, Kelly J, Finn D. In vivo modulation of LPS-induced alterations in brain and peripheral cytokines and HPA axis activity by cannabinoids. J Neuroimmunol. 2006;181:57-67 pubmed
product information
master code :
547-RL/CF
SKU :
547-RL-010/CF
product name :
Recombinant Rat IL-10 (Cys167Tyr) Protein, CF
unit size :
10 ug
description :
The Recombinant Rat IL-10 (Cys167Tyr) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Rat IL-10 (Cys167Tyr) Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-10
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in NaH2PO4 and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
theoretical molecular weight :
18.7 kDa (monomer)
gene symbol :
Il10
details of functionality :
Measured in a cell proliferation assay using MC/9-2 mouse mast cells. Thompson-Snipes, L.á et al . (1991) J. Exp. Med. 173 :507. The ED50 for this effect is 0.3-1áng/mL.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P29456
applications :
Bioactivity
source long :
E. coli -derived rat IL-10 protein Ser19-Asn178 (Cys167Tyr)
source short :
E. coli
USD :
355 USD
alt names :
CSIF, CSIFMGC126450, Cytokine synthesis inhibitory factor, GVHDS, IL10, IL10A, IL-10MGC126451, interleukin 10, interleukin-10, TGIF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.