product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Semaphorin 3B Fc Chimera Protein
catalog :
5440-S3-025
quantity :
25 ug
price :
523 USD
more info or order :
citations: 4
Reference
Xing Q, Feng J, Zhang X. Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment. Stem Cells Int. 2021;2021:6637176 pubmed publisher
Mohan V, Wade S, Sullivan C, Kasten M, Sweetman C, Stewart R, et al. Close Homolog of L1 Regulates Dendritic Spine Density in the Mouse Cerebral Cortex Through Semaphorin 3B. J Neurosci. 2019;39:6233-6250 pubmed publisher
Burk K, Mire E, Bellon A, Hocine M, Guillot J, Moraes F, et al. Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits. Nat Commun. 2017;8:14508 pubmed publisher
Arbeille E, Reynaud F, Sanyas I, Bozon M, Kindbeiter K, Causeret F, et al. Cerebrospinal fluid-derived Semaphorin3B orients neuroepithelial cell divisions in the apicobasal axis. Nat Commun. 2015;6:6366 pubmed publisher
product information
master code :
5440-S3
SKU :
5440-S3-025
product name :
Recombinant Mouse Semaphorin 3B Fc Chimera Protein
unit size :
25 ug
description :
The Recombinant Mouse Semaphorin 3B Fc Chimera Protein from R&D Systems is derived from NS0. The Recombinant Mouse Semaphorin 3B Fc Chimera Protein has been validated for the following applications: Bioactivity.
target :
Semaphorin 3B
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS and Tween« 20 with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>85%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
104-115 kDa, reducing conditions
theoretical molecular weight :
104.2 kDa (monomer)
gene symbol :
Sema3b
details of functionality :
Measured by its ability to inhibit proliferation of the A549 human lung carcinoma cells. The ED50 for this effect is 100-400 ng/mL.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
NP_033179
applications :
Bioactivity
source long :
Mouse myeloma cell line, NS0-derived mouse Semaphorin 3B protein Mouse Semaphorin 3B (Pro26 - Asp722: Arg551Ala, Arg553Ala, Arg554Ala, Arg635Ala, Arg636Ala) Accession # NP_033179 IEGRMDP Mouse IgG2A (Glu98 - Lys330) N-terminus C-terminus
source short :
NS0
USD :
523 USD
alt names :
(semaphorin) 3B, LUCA-1, SemA, Sema A(V), sema domain, immunoglobulin domain (Ig), short basic domain, secreted, Sema V, SEMA3B, sema5, SEMA5FLJ34863, SEMAA, semaphorin A, semaphorin V, semaphorin-3B, Semaphorin-V, SEMAV
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.