Recombinant Mouse IL-17A/F Heterodimer Protein | R&D Systems 5390-IL-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-17A/F Heterodimer Protein

catalog :

5390-IL-025

quantity :

25 ug

price :

434 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Zhang F, Ledue O, Jun M, Goulart C, Malley R, Lu Y. Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms. MBio. 2018;9: pubmed publisher
Ippagunta S, Gangwar R, Finkelstein D, Vogel P, Pelletier S, Gingras S, et al. Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function. Proc Natl Acad Sci U S A. 2016;113:E6162-E6171 pubmed
Kono H, Fujii H, Ogiku M, Hosomura N, Amemiya H, Tsuchiya M, et al. Role of IL-17A in neutrophil recruitment and hepatic injury after warm ischemia-reperfusion mice. J Immunol. 2011;187:4818-25 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

5390-IL

SKU :

5390-IL-025

product name :

Recombinant Mouse IL-17A/F Heterodimer Protein

Description :

The Recombinant Mouse IL-17A/F Heterodimer Protein from R&D Systems is derived from E. coli. The Recombinant Mouse IL-17A/F Heterodimer Protein has been validated for the following applications: Bioactivity.

target :

IL-17A/F Heterodimer

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

theoretical molecular weight :

14.9 kDa (IL-17A) 15.5 kDa (IL-17F), reducing conditions

details of functionality :

Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. Yao, Z. et al . (1995) Immunity 3 :811. The ED50 for this effect is 0.075-0.375 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q62386 (IL-17A) AAM77568 (IL-17F)

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse IL-17A/F Heterodimer Protein

USD :

434 USD

alt names :

CTLA8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, Cytotoxic T-Lymphocyte-Associated Protein 8, IL17, IL-17, IL-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A, interleukin-17A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage