Recombinant Rat CX3CL1/Fractalkine (Chemokine Domain) | R&D Systems 537-FT-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat CX3CL1/Fractalkine (Chemokine Domain)

catalog :

537-FT-025

quantity :

25 ug

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Jiang M, Xie H, Zhang C, Wang T, Tian H, Lu L, et al. Enhancing fractalkine/CX3CR1 signalling pathway can reduce neuroinflammation by attenuating microglia activation in experimental diabetic retinopathy. J Cell Mol Med. 2022;26:1229-1244 pubmed publisher
Clark A, Gruber Schoffnegger D, Drdla Schutting R, Gerhold K, Malcangio M, SandkÃ¼hler J. Selective activation of microglia facilitates synaptic strength. J Neurosci. 2015;35:4552-70 pubmed publisher
Husberg C, Nygard S, Finsen A, Damas J, Frigessi A, Oie E, et al. Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure. J Mol Cell Cardiol. 2008;45:261-9 pubmed publisher
Chen X, Geller E, Rogers T, Adler M. The chemokine CX3CL1/fractalkine interferes with the antinociceptive effect induced by opioid agonists in the periaqueductal grey of rats. Brain Res. 2007;1153:52-7 pubmed
Zhuang Z, Kawasaki Y, Tan P, Wen Y, Huang J, Ji R. Role of the CX3CR1/p38 MAPK pathway in spinal microglia for the development of neuropathic pain following nerve injury-induced cleavage of fractalkine. Brain Behav Immun. 2007;21:642-51 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

537-FT

SKU :

537-FT-025

product name :

Recombinant Rat CX3CL1/Fractalkine (Chemokine Domain)

Description :

The Recombinant Rat CX3CL1/Fractalkine (Chemokine Domain) from R&D Systems is derived from E. coli. The Recombinant Rat CX3CL1/Fractalkine (Chemokine Domain) has been validated for the following applications: Bioactivity.

target :

CX3CL1/Fractalkine

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

theoretical molecular weight :

8.8 kDa

gene symbol :

CX3CL1

details of functionality :

Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CX3CR1. The ED50 for this effect is 3-18 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

O55145

applications :

Bioactivity

source :

E. coli-derived Recombinant Rat CX3CL1/Fractalkine (Chemokine Domain)

USD :

396 USD

alt names :

ABCD-3, C3Xkine, chemokine (C-X3-C motif) ligand 1, CX3C membrane-anchored chemokine, CXC3, CXC3C, FKN, fractalkine, Neurotactin, neurotactin), NTNsmall inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, NTTSmall-inducible cytokine D1, SCYD1C-X3-C motif chemokine 1, small inducible cytokine subfamily D (Cys-X3-Cys), member-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage