This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Porcine IL-8/CXCL8 Protein
catalog :
535-IN
quantity :
25 ug
price :
359 USD
citations: 4
Reference
Elahi S, Thompson D, Van Kessel J, Babiuk L, Gerdts V. Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets. Infect Immun. 2017;85: pubmed publisher
Fishbourne E, Hutet E, Abrams C, Cariolet R, Le Potier M, Takamatsu H, et al. Increase in chemokines CXCL10 and CCL2 in blood from pigs infected with high compared to low virulence African swine fever virus isolates. Vet Res. 2013;44:87 pubmed publisher
Johannisson A, Jonasson R, Dernfalk J, Jensen Waern M. Simultaneous detection of porcine proinflammatory cytokines using multiplex flow cytometry by the xMAP technology. Cytometry A. 2006;69:391-5 pubmed
Brix Christensen V, Andersen S, Andersen R, Mengel A, Dyhr T, Andersen N, et al. Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model. Anesthesiology. 2004;100:861-70 pubmed
product information
brand :
R&D Systems
master code :
535-IN
SKU :
535-IN-025
product name :
Recombinant Porcine IL-8/CXCL8 Protein
description :
The Recombinant Porcine IL-8/CXCL8 Protein from R&D Systems is derived from E. coli. The Recombinant Porcine IL-8/CXCL8 Protein has been validated for the following applications: Bioactivity.
target :
CXCL8/IL-8
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Porcine
theoretical molecular weight :
9.4 kDa
gene symbol :
CXCL8
details of functionality :
Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. et al . (1987) J. Immunol. 139 :3474. The ED50 for this effect is 0.4-0.6 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is 1-5 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
catalog number base :
535-IN
accessionNumbers :
CAA43461
applications :
Bioactivity
source :
E. coli -derived porcine IL-8/CXCL8 protein Ala26-Gln104
2020 USD :
359
2021 USD :
359 USD
alt names :
3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP1, GCP-1TSG-1, IL8, interleukin 8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, member 8, MONAP, MONAPGCP1, NAF, NAP1, NAP-1NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.