Recombinant Porcine IL-8/CXCL8 Protein | R&D Systems 535-IN-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Porcine IL-8/CXCL8 Protein

catalog :

535-IN-025

quantity :

25 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Bonilla M, Fingerhut L, Alfonso Castro A, Mergani A, Schwennen C, von Köckritz Blickwede M, et al. How Long Does a Neutrophil Live?-The Effect of 24 h Whole Blood Storage on Neutrophil Functions in Pigs. Biomedicines. 2020;8: pubmed publisher
Hall S, Ison S, Owles C, Coe J, Sandercock D, Zanella A. Development and validation of a multiplex fluorescent microsphere immunoassay assay for detection of porcine cytokines. MethodsX. 2019;6:1218-1227 pubmed publisher
Elahi S, Thompson D, Van Kessel J, Babiuk L, Gerdts V. Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets. Infect Immun. 2017;85: pubmed publisher
Fishbourne E, Hutet E, Abrams C, Cariolet R, Le Potier M, Takamatsu H, et al. Increase in chemokines CXCL10 and CCL2 in blood from pigs infected with high compared to low virulence African swine fever virus isolates. Vet Res. 2013;44:87 pubmed publisher
Johannisson A, Jonasson R, Dernfalk J, Jensen Waern M. Simultaneous detection of porcine proinflammatory cytokines using multiplex flow cytometry by the xMAP technology. Cytometry A. 2006;69:391-5 pubmed
Brix Christensen V, Andersen S, Andersen R, Mengel A, Dyhr T, Andersen N, et al. Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model. Anesthesiology. 2004;100:861-70 pubmed

product information

master code :

535-IN

SKU :

535-IN-025

product name :

Recombinant Porcine IL-8/CXCL8 Protein

unit size :

25 ug

description :

The Recombinant Porcine IL-8/CXCL8 Protein from R&D Systems is derived from E. coli. The Recombinant Porcine IL-8/CXCL8 Protein has been validated for the following applications: Bioactivity.

target :

IL-8/CXCL8

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Porcine

theoretical molecular weight :

9.4 kDa

gene symbol :

CXCL8

details of functionality :

Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schr÷der, J.M. etáal . (1987) J.áImmunol. 139 :3474. The ED50 for this effect is 0.4-0.6 ╡g/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is 1-5 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

CAA43461

applications :

Bioactivity

source long :

E. coli -derived porcine IL-8/CXCL8 protein Ala26-Gln104

source short :

E. coli

USD :

456 USD

alt names :

3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP1, GCP-1TSG-1, IL8, interleukin 8, K60, LAI, LECT, LUCT, LYNAP, MDNCF, MDNCFb-ENAP, member 8, MONAP, MONAPGCP1, NAF, NAP1, NAP-1NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage