product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CCL28 Protein, CF
catalog :
533-VI-025/CF
quantity :
25 ug
price :
373 USD
more info or order :
citations: 8
Reference
Yan Y, Hu K, Fu M, Deng X, Guan X, Luo S, et al. CCL28 Enhances HSV-2 gB-Specific Th1-Polarized Immune Responses against Lethal Vaginal Challenge in Mice. Vaccines (Basel). 2022;10: pubmed publisher
Hohmann M, Habiel D, Espíndola M, Huang G, Jones I, Narayanan R, et al. Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF. JCI Insight. 2021;6: pubmed publisher
Wang P, Qi X, Xu G, Liu J, Guo J, Li X, et al. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells. Aging (Albany NY). 2019;11:7402-7415 pubmed publisher
Matsuo K, Nagakubo D, Yamamoto S, Shigeta A, Tomida S, Fujita M, et al. CCL28-Deficient Mice Have Reduced IgA Antibody-Secreting Cells and an Altered Microbiota in the Colon. J Immunol. 2018;200:800-809 pubmed publisher
Geherin S, Gómez D, Glabman R, Ruthel G, Hamann A, Debes G. IL-10+ Innate-like B Cells Are Part of the Skin Immune System and Require α4β1 Integrin To Migrate between the Peritoneum and Inflamed Skin. J Immunol. 2016;196:2514-2525 pubmed publisher
Tregoning J, Buffa V, Oszmiana A, Klein K, Walters A, Shattock R. A "prime-pull" vaccine strategy has a modest effect on local and systemic antibody responses to HIV gp140 in mice. PLoS ONE. 2013;8:e80559 pubmed publisher
Cha H, Ko H, Kim E, Chang S, Seo S, Cuburu N, et al. Mucosa-associated epithelial chemokine/CCL28 expression in the uterus attracts CCR10+ IgA plasma cells following mucosal vaccination via estrogen control. J Immunol. 2011;187:3044-52 pubmed publisher
Hieshima K, Kawasaki Y, Hanamoto H, Nakayama T, Nagakubo D, Kanamaru A, et al. CC chemokine ligands 25 and 28 play essential roles in intestinal extravasation of IgA antibody-secreting cells. J Immunol. 2004;173:3668-75 pubmed
product information
master code :
533-VI/CF
SKU :
533-VI-025/CF
product name :
Recombinant Mouse CCL28 Protein, CF
unit size :
25 ug
description :
The Recombinant Mouse CCL28 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Mouse CCL28 Protein, CF has been validated for the following applications: Bioactivity.
target :
CCL28
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
theoretical molecular weight :
12.3 kDa
gene symbol :
Ccl28
details of functionality :
Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CCR10. The ED50 for this effect is 0.3-1á╡g/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
Q9JIL2
applications :
Bioactivity
source long :
E. coli -derived mouse CCL28 protein Ile23-Arg130
source short :
E. coli
USD :
373 USD
alt names :
CCL28, chemokine (C-C motif) ligand 28, MEC, member 28, MGC71902, Protein CCK1, VIC
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.