Recombinant Mouse TGF-beta RII/(human) Fc Chimera, CF | R&D Systems 532-R2-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TGF-beta RII/(human) Fc Chimera, CF

catalog :

532-R2-050

quantity :

50 ug

price :

480 USD

citations: 4

Reference
Kissick H, Ireland D, Greay S, Beilharz M. Mechanisms of immune suppression exerted by regulatory T-cells in subcutaneous AE17 murine mesothelioma. J Interferon Cytokine Res. 2010;30:829-34 pubmed publisher
Horan G, Wood S, Ona V, Li D, Lukashev M, Weinreb P, et al. Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation. Am J Respir Crit Care Med. 2008;177:56-65 pubmed
Close J, Gumuscu B, Reh T. Retinal neurons regulate proliferation of postnatal progenitors and Müller glia in the rat retina via TGF beta signaling. Development. 2005;132:3015-26 pubmed
Zamiri P, Masli S, Kitaichi N, Taylor A, Streilein J. Thrombospondin plays a vital role in the immune privilege of the eye. Invest Ophthalmol Vis Sci. 2005;46:908-19 pubmed

product information

master code :

532-R2

SKU :

532-R2-050

product name :

Recombinant Mouse TGF-beta RII/(human) Fc Chimera, CF

unit size :

50 ug

description :

The Recombinant Mouse TGF-beta RII/(human) Fc Chimera, CF from R&D Systems is derived from NS0. The Recombinant Mouse TGF-beta RII/(human) Fc Chimera, CF has been validated for the following applications: Bioactivity.

target :

TGF-beta RII

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

60-65 kDa, reducing conditions

theoretical molecular weight :

44.6 kDa (monomer)

gene symbol :

Tgfbr2

details of functionality :

Measured by its ability to inhibit TGF┐▀1 activity on HT-2 mouse T cells. Tsang,áM. etáal . (1995) Cytokine 7 :389. The ED50 for this effect is 10-70 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q62312.1

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse TGF-beta RII protein Mouse TGF┐▀ RII (Ile24-Asp184) Accession # Q62312.1 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

480 USD

alt names :

AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbetaRII, TGFbeta-RII, TGFBR2, TGF-bRII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.