Recombinant Mouse IL-4R alpha Fc Chimera Protein, CF | R&D Systems 530-MR-100 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IL-4R alpha Fc Chimera Protein, CF

catalog :

530-MR-100

quantity :

100 ug

price :

518 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Diogo G, Sparrow A, Paul M, Copland A, Hart P, Stelter S, et al. Murine IL-4?2 splice variant down-regulates IL-4 activities independently of IL-4R? binding and STAT-6 phosphorylation. Cytokine. 2017;99:154-162 pubmed publisher
Venmar K, Carter K, Hwang D, Dozier E, Fingleton B. IL4 receptor ILR4α regulates metastatic colonization by mammary tumors through multiple signaling pathways. Cancer Res. 2014;74:4329-40 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

530-MR

SKU :

530-MR-100

product name :

Recombinant Mouse IL-4R alpha Fc Chimera Protein, CF

Description :

The Recombinant Mouse IL-4R alpha Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse IL-4R alpha Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-4R alpha

category :

Proteins and Enzymes

unit size :

100 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

65-85 kDa, reducing conditions

theoretical molecular weight :

51 kDa

gene symbol :

Il4ra

details of functionality :

Measured by its ability to inhibit the IL-4-dependent proliferation of HT-2 mouse T cells. Tsang, M. et al . (1995) Cytokine 7 :389. The ED50 for this effect is 0.05-0.2 µg/mL in the presence of 3 ng/mL of recombinant mouse IL-4.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q544A9

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse IL-4R alpha Fc Chimera Protein

USD :

518 USD

alt names :

CD124, CD124 antigen, IL-4 R alpha, IL-4 receptor subunit alpha, IL4R, IL4R alpha, IL-4R subunit alpha, IL-4RA, IL4RACD124, IL-4R-alpha, interleukin 4 receptor, interleukin-4 receptor alpha chain, interleukin-4 receptor subunit alpha

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage