Recombinant Human Neurexin 1 beta Fc Chimera Protein, CF | R&D Systems 5268-NX-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Neurexin 1 beta Fc Chimera Protein, CF

catalog :

5268-NX-050

quantity :

50 ug

price :

536 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Wierda K, Toft Bertelsen T, Gøtzsche C, Pedersen E, Korshunova I, Nielsen J, et al. The soluble neurexin-1β ectodomain causes calcium influx and augments dendritic outgrowth and synaptic transmission. Sci Rep. 2020;10:18041 pubmed publisher
Kashiwagi Y, Higashi T, Obashi K, Sato Y, Komiyama N, Grant S, et al. Computational geometry analysis of dendritic spines by structured illumination microscopy. Nat Commun. 2019;10:1285 pubmed publisher
Naito Y, Tanabe Y, Lee A, Hamel E, Takahashi H. Amyloid-β Oligomers Interact with Neurexin and Diminish Neurexin-mediated Excitatory Presynaptic Organization. Sci Rep. 2017;7:42548 pubmed publisher

product information

master code :

5268-NX

SKU :

5268-NX-050

product name :

Recombinant Human Neurexin 1 beta Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human Neurexin 1 beta Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Neurexin 1 beta Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

Neurexin 1 beta/NXRN1b

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

85-95 kDa, reducing conditions

theoretical molecular weight :

59.9 kDa (monomer)

gene symbol :

NRXN1

details of functionality :

Measured by its binding ability in a functional ELISA. Biotinylated recombinant rat NLGN-1v2 immobilized on a streptavidin-coated plate at 1 ╡g/mL (100 ╡L/well) can bind Recombinant Human Neurexin 1▀/NXRN1b Fc Chimera with an apparent Kd 4 nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_620072

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived human Neurexin 1 beta/NXRN1b protein Human Neurexin 1▀ (Ala51-Ser363) Accession # NP_620072 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

536 USD

alt names :

Hs.22998, NXR1B, NXRN1b, PTHSL2, SCZD17

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage