product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Notch-1 Fc Chimera Protein, CF
catalog :
5267-TK-050
quantity :
50 ug
price :
423 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Nandagopal N, Santat L, Lebon L, Sprinzak D, Bronner M, Elowitz M. Dynamic Ligand Discrimination in the Notch Signaling Pathway. Cell. 2018;172:869-880.e19 pubmed publisher
Lebon L, Lee T, Sprinzak D, Jafar Nejad H, Elowitz M. Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states. elife. 2014;3:e02950 pubmed publisher
Benner E, Luciano D, Jo R, Abdi K, Paez Gonzalez P, Sheng H, et al. Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. Nature. 2013;497:369-73 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
5267-TK
SKU :
5267-TK-050
product name :
Recombinant Mouse Notch-1 Fc Chimera Protein, CF
Description :
The Recombinant Mouse Notch-1 Fc Chimera Protein, CF from R&D Systems is derived from CHO. The Recombinant Mouse Notch-1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
Notch-1
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS and EDTA.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
110-120 kDa, reducing conditions
theoretical molecular weight :
80.7 kDa (monomer)
details of functionality :
Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse Notch-1 Fc Chimera at 2 µg/mL (100 µL/mL) can bind Recombinant Rat Jagged 1 Fc Chimera (Catalog # 599-JG) with an apparent KD 2 nM.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAM28905
applications :
Binding Activity
source :
CHO-derived Recombinant Mouse Notch-1 Fc Chimera Protein
USD :
423 USD
alt names :
EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, Notch1, TAN1, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.