This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human ENPP-2/Autotaxin Protein, CF
catalog :
5255-EN
quantity :
10 ug
price :
339 USD
citations: 5
Reference
Sakai N, Bain G, Furuichi K, Iwata Y, Nakamura M, Hara A, et al. The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage. Sci Rep. 2019;9:7414 pubmed publisher
Pleli T, Mondorf A, Ferreirós N, Thomas D, Dvorak K, Biondi R, et al. Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors. Cell Physiol Biochem. 2018;45:2516-2528 pubmed publisher
She S, Yang M, Hu H, Hu P, Yang Y, Ren H. Proteomics Based Identification of Autotaxin As An Anti-Hepatitis B Virus Factor and a Promoter of Hepatoma Cell Invasion and Migration. Cell Physiol Biochem. 2018;45:744-760 pubmed publisher
Zhang G, Cheng Y, Zhang Q, Li X, Zhou J, Wang J, et al. ATX?LPA axis facilitates estrogen?induced endometrial cancer cell proliferation via MAPK/ERK signaling pathway. Mol Med Rep. 2018;17:4245-4252 pubmed publisher
Ryu J, Han H. Autotaxin-LPA axis regulates hMSC migration by adherent junction disruption and cytoskeletal rearrangement via LPAR1/3-dependent PKC/GSK3β/β-catenin and PKC/Rho GTPase pathways. Stem Cells. 2015;33:819-32 pubmed publisher
product information
brand :
R&D Systems
master code :
5255-EN
SKU :
5255-EN-010
product name :
Recombinant Human ENPP-2/Autotaxin Protein, CF
description :
The Recombinant Human ENPP-2/Autotaxin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human ENPP-2/Autotaxin Protein, CF has been validated for the following applications: Enzyme Activity.
target :
ENPP-2/Autotaxin
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Supplied as a 0.2 µm filtered solution in Tris and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
99 kDa and 103 kDa, migrates as a doublet under reducing conditions
theoretical molecular weight :
94 kDa
gene symbol :
ENPP2
details of functionality :
Measured by its ability to cleave Bis (p-Nitrophenyl) Phosphate (BPNPP). The specific activity is 8,000 pmol/min/µg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
5255-EN
accessionNumbers :
Q13822
applications :
Enzyme Activity
source :
Mouse myeloma cell line, NS0-derived human ENPP-2/Autotaxin protein Asp49-Ile863, with an N-terminal 6-His tag
2020 USD :
339
2021 USD :
339 USD
alt names :
ATX, ATXFLJ26803, ATX-X, AUTOTAXIN, autotaxin-t, EC 3.1.4.39, ectonucleotide pyrophosphatase/phosphodiesterase 2, ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, ENPP2, Extracellular lysophospholipase D, Lysophosphatidic Acid, LysoPLD, NPP2, PD-IALPHA, PDNP2, PDNP2NPP2, phosphodiesterase I/nucleotide pyrophosphatase 2, plasma lysophospholipase D
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.