Recombinant Human ENPP-2/Autotaxin Protein, CF | R&D Systems 5255-EN-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human ENPP-2/Autotaxin Protein, CF

catalog :

5255-EN-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Sakai N, Bain G, Furuichi K, Iwata Y, Nakamura M, Hara A, et al. The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage. Sci Rep. 2019;9:7414 pubmed publisher
Pleli T, Mondorf A, Ferreirós N, Thomas D, Dvorak K, Biondi R, et al. Activation of Adenylyl Cyclase Causes Stimulation of Adenosine Receptors. Cell Physiol Biochem. 2018;45:2516-2528 pubmed publisher
She S, Yang M, Hu H, Hu P, Yang Y, Ren H. Proteomics Based Identification of Autotaxin As An Anti-Hepatitis B Virus Factor and a Promoter of Hepatoma Cell Invasion and Migration. Cell Physiol Biochem. 2018;45:744-760 pubmed publisher
Zhang G, Cheng Y, Zhang Q, Li X, Zhou J, Wang J, et al. ATX?LPA axis facilitates estrogen?induced endometrial cancer cell proliferation via MAPK/ERK signaling pathway. Mol Med Rep. 2018;17:4245-4252 pubmed publisher
Ryu J, Han H. Autotaxin-LPA axis regulates hMSC migration by adherent junction disruption and cytoskeletal rearrangement via LPAR1/3-dependent PKC/GSK3Î²/Î²-catenin and PKC/Rho GTPase pathways. Stem Cells. 2015;33:819-32 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

5255-EN

SKU :

5255-EN-010

product name :

Recombinant Human ENPP-2/Autotaxin Protein, CF

description :

The Recombinant Human ENPP-2/Autotaxin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human ENPP-2/Autotaxin Protein, CF has been validated for the following applications: Enzyme Activity.

target :

ENPP-2/Autotaxin

unit size :

10 ug

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 µm filtered solution in Tris and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

observed molecular weight :

99 kDa and 103 kDa, migrates as a doublet under reducing conditions

theoretical molecular weight :

94 kDa

gene symbol :

ENPP2

details of functionality :

Measured by its ability to cleave Bis (p-Nitrophenyl) Phosphate (BPNPP). The specific activity is 8,000 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q13822

applications :

Enzyme Activity

product keywords :

5255-EN, rhENPP-2, hENPP-2, carrier-free, carrier free, 5255EN, kinasesphosphatases, ENPP2, ENPP 2, ENPP2, Ectonucleotide Pyrophosphatase/Phosphodiesterase 2, Ectonucleotide, Pyrophosphatase/Phosphodiesterase2, NPP2, NPP 2, PDNP2, PDNP 2, ATX, Plasma Lysophospholipase D, LysoPLD

source :

NS0-derived Recombinant Human ENPP-2/Autotaxin Protein, CF

USD :

423

USD 2025 :

432 USD

alt names :

ATX, ATXFLJ26803, ATX-X, AUTOTAXIN, autotaxin-t, EC 3.1.4.39, ectonucleotide pyrophosphatase/phosphodiesterase 2, ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, ENPP2, Extracellular lysophospholipase D, Lysophosphatidic Acid, LysoPLD, NPP2, PD-IALPHA, PDNP2, PDNP2NPP2, phosphodiesterase I/nucleotide pyrophosphatase 2, plasma lysophospholipase D

more info or order :

R&D Systems product webpage