product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat CXCL2/CINC-3 Protein, CF
catalog :
525-C3-025/CF
quantity :
25 ug
price :
273 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Sun J, Pan X, Christiansen L, Yuan X, Skovgaard K, Chatterton D, et al. Necrotizing enterocolitis is associated with acute brain responses in preterm pigs. J Neuroinflammation. 2018;15:180 pubmed publisher
Miura T, Wang J, Holmes K, Mason R. Rat coronaviruses infect rat alveolar type I epithelial cells and induce expression of CXC chemokines. Virology. 2007;369:288-98 pubmed
Fan X, Patera A, Pong Kennedy A, Deno G, Gonsiorek W, Manfra D, et al. Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8. J Biol Chem. 2007;282:11658-66 pubmed
Watts J, Zagorski J, Gellar M, Stevinson B, Kline J. Cardiac inflammation contributes to right ventricular dysfunction following experimental pulmonary embolism in rats. J Mol Cell Cardiol. 2006;41:296-307 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
525-C3/CF
SKU :
525-C3-025/CF
product name :
Recombinant Rat CXCL2/CINC-3 Protein, CF
Description :
The Recombinant Rat CXCL2/CINC-3 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Rat CXCL2/CINC-3 Protein, CF has been validated for the following applications: Bioactivity.
target :
CXCL2/GRO beta/MIP-2/CINC-3
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
theoretical molecular weight :
7.6 kDa
gene symbol :
Cxcl2
details of functionality :
Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. et al . (1987) J. Immunol. 139 :3474. The ED50 for this effect is 1-3 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is 5-25 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P30348.1
applications :
Bioactivity
source :
E. coli-derived Recombinant Rat CXCL2/CINC-3 Protein
USD :
273 USD
alt names :
chemokine (C-X-C motif) ligand 2, CINC-2a, CINC3, CINC-3, C-X-C Motif Chemokine 2, GRO beta, GRO2, GRO2 oncogene, GROb, Gro-beta, Growth-regulated protein beta, Macrophage inflammatory protein 2-alpha, melanoma growth stimulatory activity beta, MGSA beta, MGSA-b, MGSA-beta, MIP2, MIP-2, MIP-2a, MIP2A, MIP2-alpha, SCYB2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.