product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera Protein, CF
catalog :
5235-S4B-050
quantity :
50 ug
price :
423 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Vilallongue N, Schaeffer J, Hesse A, Delpech C, Blot B, Paccard A, et al. Guidance landscapes unveiled by quantitative proteomics to control reinnervation in adult visual system. Nat Commun. 2022;13:6040 pubmed publisher
Mediero A, Wilder T, Shah L, Cronstein B. Adenosine A2A receptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis. FASEB J. 2018;32:3487-3501 pubmed publisher
Zielonka M, Krishnan R, Swiercz J, Offermanns S. The IκB kinase complex is required for plexin-B-mediated activation of RhoA. PLoS ONE. 2014;9:e105661 pubmed publisher
image
image 1 :
R&D Systems 5235-S4B-050 image 1
Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera Protein Binding Activity
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
5235-S4B
SKU :
5235-S4B-050
product name :
Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera Protein, CF
Description :
The Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Semaphorin 4D/CD100
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Supplied as a 0.2 µm filtered solution in Tris and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Mouse
observed molecular weight :
105-135 kDa, under reducing conditions
theoretical molecular weight :
103 kDa
details of functionality :
Measured by its binding ability in a functional ELISA. When Recombinant Human Plexin B2 (Catalog # 5329-PB ) is coated at 5 µg/mL, Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera binds with an ED50 of 4-24 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
NP_038688.2
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera Protein
USD :
423 USD
alt names :
A8, BB18, CD100, CD100 antigen, CD100M-sema-G, coll-4, FLJ33485, FLJ34282, FLJ39737, FLJ46484, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, 4D, MGC169138, MGC169141, M-sema-G, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4D, SEMA4D, SEMAJ, semaphorin-4D
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening. 3 months, -70 °C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.