Recombinant Rat GM-CSF Protein | R&D Systems 518-GM-005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat GM-CSF Protein

catalog :

518-GM-005

quantity :

5 ug (also 25 ug)

price :

165 USD

citations: 10

Reference
Lazarevi x107 M, Stegnjai x107 G, Jevti x107 B, Despotovi x107 S, Ignjatovi x107 x, Stanisavljevi x107 S, et al. Increased regulatory activity of intestinal innate lymphoid cells type 3 (ILC3) prevents experimental autoimmune encephalomyelitis severity. J Neuroinflammation. 2024;21:26 pubmed publisher
Kim S, Son Y. Astrocytes Stimulate Microglial Proliferation and M2 Polarization In Vitro through Crosstalk between Astrocytes and Microglia. Int J Mol Sci. 2021;22: pubmed publisher
Jones I, Haese N, Gatault P, Streblow Z, Andoh T, Denton M, et al. Rat Cytomegalovirus Virion-Associated Proteins R131 and R129 Are Necessary for Infection of Macrophages and Dendritic Cells. Pathogens. 2020;9: pubmed publisher
Lim J, Chung E, Son Y. A neuropeptide, Substance-P, directly induces tissue-repairing M2 like macrophages by activating the PI3K/Akt/mTOR pathway even in the presence of IFNγ. Sci Rep. 2017;7:9417 pubmed publisher
Lee H, Liu S, Lin C, Lee S, Hsu C, Sytwu H, et al. A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke. Theranostics. 2017;7:855-875 pubmed publisher
Lazzaro M, Bettegazzi B, Barbariga M, Codazzi F, Zacchetti D, Alessio M. Ceruloplasmin potentiates nitric oxide synthase activity and cytokine secretion in activated microglia. J Neuroinflammation. 2014;11:164 pubmed publisher
Slater B, Vilson F, Guo Y, Weinreich D, Hwang S, Bernstein S. Optic nerve inflammation and demyelination in a rodent model of nonarteritic anterior ischemic optic neuropathy. Invest Ophthalmol Vis Sci. 2013;54:7952-61 pubmed publisher
Quan Y, Jiang J, Dingledine R. EP2 receptor signaling pathways regulate classical activation of microglia. J Biol Chem. 2013;288:9293-302 pubmed publisher
Krejci P, Prochazkova J, Bryja V, Jelinkova P, Pejchalova K, Kozubik A, et al. Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes. Cell Signal. 2009;21:151-60 pubmed publisher
Reed J, Clegg D, Smith K, Tolod Richer E, Matter E, Picard L, et al. GM-CSF action in the CNS decreases food intake and body weight. J Clin Invest. 2005;115:3035-44 pubmed

product information

master code :

518-GM

SKU :

518-GM-005

product name :

Recombinant Rat GM-CSF Protein

unit size :

5 ug (also 25 ug)

description :

The Recombinant Rat GM-CSF Protein from R&D Systems is derived from E. coli. The Recombinant Rat GM-CSF Protein has been validated for the following applications: Bioactivity.

target :

GM-CSF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

theoretical molecular weight :

14.7 kDa

gene symbol :

Csf2

details of functionality :

Measured in a cell proliferation assay using DA3 mouse myeloma cells. The ED50 for this effect is 5-30 pg/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P48750.1

applications :

Bioactivity

source long :

E. coli -derived rat GM-CSF protein Ala1-Lys127, with and without an N-terminal Met

source short :

E. coli

USD :

165 USD

alt names :

colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, CSF2, CSF-2, GMCSF, GM-CSF, GMCSFgranulocyte-macrophage colony-stimulating factor, granulocyte-macrophage colony stimulating factor, MGC131935, MGC138897, Molgramostim, molgramostin, sargramostim

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.