Recombinant Human Neuroligin 4/NLGN4 Protein, CF | R&D Systems 5158-NL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Neuroligin 4/NLGN4 Protein, CF

catalog :

5158-NL-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Yumoto T, Kimura M, Nagatomo R, Sato T, Utsunomiya S, Aoki N, et al. Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanisms. Mol Autism. 2020;11:68 pubmed publisher
Venkatesh H, Tam L, Woo P, Lennon J, Nagaraja S, Gillespie S, et al. Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma. Nature. 2017;549:533-537 pubmed publisher

product information

master code :

5158-NL

SKU :

5158-NL-050

product name :

Recombinant Human Neuroligin 4/NLGN4 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Neuroligin 4/NLGN4 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Neuroligin 4/NLGN4 Protein, CF has been validated for the following applications: Bioactivity.

target :

Neuroligin 4X/NLGN4X

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

90-100 kDa, reducing conditions

theoretical molecular weight :

72.2 kDa

gene symbol :

NLGN4X

details of functionality :

Measured by its ability to enhance neurite outgrowth of dissociated E13 chick embryonic dorsal root ganglia (DRG) neurons. Able to significantly enhance neurite outgrowth when immobilized at 3-12 ╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_065793

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Neuroligin 4X/NLGN4X protein Gln42-Ser676, with a C-terminal 6-His tag

source short :

NS0

USD :

456 USD

alt names :

ASPGX2, AUTSX2, HLNX, HNL4X, HNLX, KIAA1260AUTSX2, MGC22376, neuroligin 4, X-linked, NL4, NLGN, NLGN4, NLGN4neuroligin 4, NLGN4X, X-linked

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage