Recombinant Rat CXCL1/CINC-1 Protein, CF | R&D Systems 515-CN-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat CXCL1/CINC-1 Protein, CF

catalog :

515-CN-010/CF

quantity :

10 ug (also 50 ug)

price :

249 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Murata M, Noda K, Yoshida S, Saito M, Fujiya A, Kanda A, et al. Unsaturated Aldehyde Acrolein Promotes Retinal Glial Cell Migration. Invest Ophthalmol Vis Sci. 2019;60:4425-4435 pubmed publisher
Ni H, Wang Y, An K, Liu Q, Xu L, Zhu C, et al. Crosstalk between NFκB-dependent astrocytic CXCL1 and neuron CXCR2 plays a role in descending pain facilitation. J Neuroinflammation. 2019;16:1 pubmed publisher
Suzukawa K, Tomlin J, Pak K, Chavez E, Kurabi A, Baird A, et al. A mouse model of otitis media identifies HB-EGF as a mediator of inflammation-induced mucosal proliferation. PLoS ONE. 2014;9:e102739 pubmed publisher
Russo T, Beanan J, Olson R, Macdonald U, Luke N, Gill S, et al. Rat pneumonia and soft-tissue infection models for the study of Acinetobacter baumannii biology. Infect Immun. 2008;76:3577-86 pubmed publisher
Fan X, Patera A, Pong Kennedy A, Deno G, Gonsiorek W, Manfra D, et al. Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8. J Biol Chem. 2007;282:11658-66 pubmed
Rhodes K, Raivich G, Fawcett J. The injury response of oligodendrocyte precursor cells is induced by platelets, macrophages and inflammation-associated cytokines. Neuroscience. 2006;140:87-100 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

515-CN/CF

SKU :

515-CN-010/CF

product name :

Recombinant Rat CXCL1/CINC-1 Protein, CF

Description :

The Recombinant Rat CXCL1/CINC-1 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Rat CXCL1/CINC-1 Protein, CF has been validated for the following applications: Bioactivity.

target :

CXCL1/GRO alpha/KC/CINC-1

category :

Proteins and Enzymes

unit size :

10 ug (also 50 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Rat

theoretical molecular weight :

7.8 kDa

gene symbol :

Cxcl1

details of functionality :

Measured by its ability to induce myeloperoxidase release from cytochalasin B-treated human neutrophils. Schröder, J.M. et al . (1987) J. Immunol. 139 :3474. The ED50 for this effect is 0.1-0.3 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CXCR2. The ED50 for this effect is 0.2-1 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P14095

applications :

Bioactivity

source :

E. coli-derived Recombinant Rat CXCL1/CINC-1 Protein

USD :

249 USD

alt names :

CINC1, CINC-1, FSP, GRO alpha, GRO1, GROa, KC, MGSA, MGSA-a, MGSA-alpha, NAP-3, SCYB1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage