Recombinant Human SMOC-2 Protein, CF | R&D Systems 5140-SM-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human SMOC-2 Protein, CF

catalog :

5140-SM-050

quantity :

50 ug

price :

550 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Feng D, Gao P, Henley N, Dubuissez M, Chen N, Laurin L, et al. SMOC2 promotes an epithelial-mesenchymal transition and a pro-metastatic phenotype in epithelial cells of renal cell carcinoma origin. Cell Death Dis. 2022;13:639 pubmed publisher
Jang B, Kim H, Bae J, Kim W, Kim H, Kang G. SMOC2, an intestinal stem cell marker, is an independent prognostic marker associated with better survival in colorectal cancers. Sci Rep. 2020;10:14591 pubmed publisher
Thomas J, Chhuy Hy L, Andrykovich K, Moos M. SMOC Binds to Pro-EGF, but Does Not Induce Erk Phosphorylation via the EGFR. PLoS ONE. 2016;11:e0154294 pubmed publisher
Brellier F, Ruggiero S, Zwolanek D, Martina E, Hess D, Brown Luedi M, et al. SMOC1 is a tenascin-C interacting protein over-expressed in brain tumors. Matrix Biol. 2011;30:225-33 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

5140-SM

SKU :

5140-SM-050

product name :

Recombinant Human SMOC-2 Protein, CF

Description :

The Recombinant Human SMOC-2 Protein, CF from R&D Systems is derived from CHO. The Recombinant Human SMOC-2 Protein, CF has been validated for the following applications: Bioactivity.

target :

SMOC-2

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

58-66 kDa, reducing conditions

theoretical molecular weight :

48.3 kDa

gene symbol :

SMOC2

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of A431 human epithelial carcinoma cells. When 5 x 104 cells/well are added to rhSMOC-2 coated plates, cell adhesion is enhanced in a dose dependent manner after 75 minutes at 37 °C. The ED50 for this effect is 0.4-1.6 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAH47583

applications :

Bioactivity

source :

CHO-derived Recombinant Human SMOC-2 Protein

USD :

550 USD

alt names :

bA270C4A.1, bA37D8.1, dJ421D16.1, MST117, MSTP117, MSTP140, SMAP2, SMAP-2, SMAP2Secreted modular calcium-binding protein 2, SMOC2, SMOC-2, smooth muscle associated protein 2, Smooth muscle-associated protein 2, SPARC related modular calcium binding 2, SPARC-related modular calcium-binding protein 2, thyroglobulin type-1 repeat containing protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage