Recombinant Human MMP-3 Protein, CF | R&D Systems 513-MP-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human MMP-3 Protein, CF

catalog :

513-MP-010

quantity :

10 ug

price :

444 USD

more info or order :

R&D Systems product webpage

citations: 10

Reference
Levengood M, Carosino C, Zhang X, Lucas S, Ortiz D, Westendorf L, et al. Preclinical development of SGN-CD47M: Protease-activated antibody technology enables selective tumor targeting of the innate immune checkpoint receptor CD47. Mol Cancer Ther. 2024;: pubmed publisher
Roberts K, Cubitt M, Carlton T, Rodrigues Duarte L, Maggiore L, Chai R, et al. Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease. Sci Rep. 2021;11:19422 pubmed publisher
Alania Y, Creighton J, Trevelin L, Zamperini C, Bedran Russo A. Regional contribution of proteoglycans to the fracture toughness of the dentin extracellular matrix. J Biomech. 2020;101:109633 pubmed publisher
Devel L, Almer G, Cabella C, Beau F, Bernes M, Oliva P, et al. Biodistribution of Nanostructured Lipid Carriers in Mice Atherosclerotic Model. Molecules. 2019;24: pubmed publisher
Crowe J, Roberts K, Carlton T, Maggiore L, Cubitt M, Clare S, et al. Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease. Sci Rep. 2018;8:4941 pubmed publisher
MikuÅ‚a Pietrasik J, Uruski P, SosiÅ„ska P, Maksin K, Piotrowska Kempisty H, KuciÅ„ska M, et al. Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases. Cell Death Dis. 2016;7:e2565 pubmed publisher
Djokic J, Fagotto Kaufmann C, Bartels R, Nelea V, Reinhardt D. Fibulin-3, -4, and -5 are highly susceptible to proteolysis, interact with cells and heparin, and form multimers. J Biol Chem. 2013;288:22821-35 pubmed publisher
Devel L, Beau F, Amoura M, Vera L, Cassar Lajeunesse E, Garcia S, et al. Simple pseudo-dipeptides with a P2' glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins. J Biol Chem. 2012;287:26647-56 pubmed publisher
Zhao X, Qureshi F, Eastman P, Manning W, Alexander C, Robinson W, et al. Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis. J Immunol Methods. 2012;378:72-80 pubmed publisher
Zhou B, Peyton M, He B, Liu C, Girard L, Caudler E, et al. Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer. Cancer Cell. 2006;10:39-50 pubmed

product information

master code :

513-MP

SKU :

513-MP-010

product name :

Recombinant Human MMP-3 Protein, CF

unit size :

10 ug

description :

The Recombinant Human MMP-3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human MMP-3 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

MMP-3

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in MES, NaCl, CaCl2, Glycerol and Brij-35.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

54-56 kDa doublet, reducing conditions

theoretical molecular weight :

52 kDa

gene symbol :

MMP3

details of functionality :

Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Catalog # ES002 ). The specific activity is 150 pmol/min/╡g, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P08254

applications :

Enzyme Activity

source long :

Mouse myeloma cell line, NS0-derived human MMP-3 protein Tyr18-Cys477 (Lys45Glu)

source short :

NS0

USD :

444 USD

alt names :

CHDS6, EC 3.4.24, EC 3.4.24.17, matrix metallopeptidase 3 (stromelysin 1, progelatinase), matrix metalloproteinase 3 (stromelysin 1, progelatinase), Matrix metalloproteinase-3, MGC126102, MGC126103, MMP3, MMP-3, proteoglycanase, SL-1, STMY, STMY1MGC126104, STR1, Stromelysin 1, stromelysin-1, Transin-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage