Recombinant Human CCL23/Ck beta 8-1 (aa 46-137) Protein, CF | R&D Systems 508-CK-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CCL23/Ck beta 8-1 (aa 46-137) Protein, CF

catalog :

508-CK-025/CF

quantity :

25 ug

price :

252 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Kim J, Kim Y, Ko J. CK beta 8/CCL23 induces cell migration via the Gi/Go protein/PLC/PKC delta/NF-kappa B and is involved in inflammatory responses. Life Sci. 2010;86:300-8 pubmed publisher
Miao Z, Premack B, Wei Z, Wang Y, Gerard C, Showell H, et al. Proinflammatory proteases liberate a discrete high-affinity functional FPRL1 (CCR12) ligand from CCL23. J Immunol. 2007;178:7395-404 pubmed
Boldt K, Rist W, Weiss S, Weith A, Lenter M. FPRL-1 induces modifications of migration-associated proteins in human neutrophils. Proteomics. 2006;6:4790-9 pubmed

product information

master code :

508-CK/CF

SKU :

508-CK-025/CF

product name :

Recombinant Human CCL23/Ck beta 8-1 (aa 46-137) Protein, CF

unit size :

25 ug

description :

The Recombinant Human CCL23/Ck beta 8-1 (aa 46-137) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human CCL23/Ck beta 8-1 (aa 46-137) Protein, CF has been validated for the following applications: Bioactivity.

target :

CCL23/Ck beta 8-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

10.5 kDa

gene symbol :

CCL23

details of functionality :

Measured by its ability to chemoattract THP-1 human acute monocytic leukemia cells. The ED50 for this effect is 0.01-0.04á╡g/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR1. The ED50 for this effect is 0.002-0.01á╡g/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAC63327

applications :

Bioactivity

source long :

E. coli -derived human CCL23/Ck beta 8-1 protein Met46-Asn137

source short :

E. coli

USD :

252 USD

alt names :

C6 beta-chemokine, chemokine (C-C motif) ligand 23, Ck beta 8-1, CKb8, CKB-8, Ckb81, CK-beta-8, hmrp-2a, Macrophage inflammatory protein 3, MIP3, MIP-3CK-BETA-8, MPIF1, MPIF-1Ckb-8-1, Myeloid progenitor inhibitory factor 1, SCYA23C-C motif chemokine 23, small inducible cytokine subfamily A (Cys-Cys), member 23, Small-inducible cytokine A23

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage