Recombinant Rat IL-2 Protein, CF | R&D Systems 502-RL-010/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat IL-2 Protein, CF

catalog :

502-RL-010/CF

quantity :

10 ug (also 50 ug)

price :

286 USD

citations: 12

Reference
Weatherly L, Shane H, Baur R, Lukomska E, Roberts J, Fedan J, et al. Biological effects of inhaled crude oil. VI. Immunotoxicity. Toxicol Appl Pharmacol. 2022;449:116100 pubmed publisher
Zhu Z, Han C, Xian S, Zhuang F, Ding F, Zhang W, et al. Placental Mesenchymal Stromal Cells (PMSCs) and PMSC-Derived Extracellular Vesicles (PMSC-EVs) Attenuated Renal Fibrosis in Rats with Unilateral Ureteral Obstruction (UUO) by Regulating CD4+ T Cell Polarization. Stem Cells Int. 2020;2020:2685820 pubmed publisher
Li Q, Cao Q, Wang C, Nguyen H, Wang X, Zheng G, et al. Dendritic cell-targeted CD40 DNA vaccine suppresses Th17 and ameliorates progression of experimental autoimmune glomerulonephritis. J Leukoc Biol. 2019;105:809-819 pubmed publisher
Lee H, Liu S, Lin C, Lee S, Hsu C, Sytwu H, et al. A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke. Theranostics. 2017;7:855-875 pubmed publisher
Nishioka Y, Yamaguchi M, Kawakami A, Munehiro M, Masuda S, Tomaru U, et al. Type II Natural Killer T Cells that Recognize Sterol Carrier Protein 2 Are Implicated in Vascular Inflammation in the Rat Model of Systemic Connective Tissue Diseases. Am J Pathol. 2017;187:176-186 pubmed publisher
Siddiqui T, Lively S, Ferreira R, Wong R, Schlichter L. Expression and contributions of TRPM7 and KCa2.3/SK3 channels to the increased migration and invasion of microglia in anti-inflammatory activation states. PLoS ONE. 2014;9:e106087 pubmed publisher
Martinelli R, Zeiger A, Whitfield M, Sciuto T, Dvorak A, Van Vliet K, et al. Probing the biomechanical contribution of the endothelium to lymphocyte migration: diapedesis by the path of least resistance. J Cell Sci. 2014;127:3720-34 pubmed publisher
Karrenbauer B, Ho Y, Ludwig V, Löhn J, Spanagel R, Schwarting R, et al. Time-dependent effects of striatal interleukin-2 on open field behaviour in rats. J Neuroimmunol. 2009;208:10-8 pubmed publisher
Krejci P, Prochazkova J, Bryja V, Jelinkova P, Pejchalova K, Kozubik A, et al. Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes. Cell Signal. 2009;21:151-60 pubmed publisher
Foulds L, Boysen R, Crane M, Yang Y, Muir J, Smith A, et al. Molecular identification of lyso-glycerophosphocholines as endogenous immunosuppressives in bovine and rat gonadal fluids. Biol Reprod. 2008;79:525-36 pubmed publisher
Oh J, Kim M, Shin M, Lee H, Ko J, Wee W, et al. The anti-inflammatory and anti-angiogenic role of mesenchymal stem cells in corneal wound healing following chemical injury. Stem Cells. 2008;26:1047-55 pubmed publisher
Conant S, Swanborg R. Autoreactive T cells persist in rats protected against experimental autoimmune encephalomyelitis and can be activated through stimulation of innate immunity. J Immunol. 2004;172:5322-8 pubmed

product information

master code :

502-RL/CF

SKU :

502-RL-010/CF

product name :

Recombinant Rat IL-2 Protein, CF

unit size :

10 ug (also 50 ug)

description :

The Recombinant Rat IL-2 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Rat IL-2 Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-2

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in Ammonium Acetate and Glycerol.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

theoretical molecular weight :

16 kDa

gene symbol :

Il2

details of functionality :

Measured in a cell proliferation assay using CTLL-2 mouse cytotoxic T cells. Gearing, A.J.H. and C.B. Bird (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 295. The ED50 for this effect is 0.04-0.2 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P17108

applications :

Bioactivity

source long :

E. coli -derived rat IL-2 protein Ala21-Gln155, with and without an N-terminal Met

source short :

E. coli

USD :

286 USD

alt names :

aldesleukin, IL2, IL-2, IL-2lymphokine, interleukin 2, interleukin-2, involved in regulation of T-cell clonal expansion, Proleukin, T cell growth factor, T-cell growth factor, TCGF

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after opening.