Recombinant Mouse VEGF 120 Protein | R&D Systems 494-VE-005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse VEGF 120 Protein

catalog :

494-VE-005

quantity :

5 ug (also 25 ug)

price :

373 USD

citations: 9

Reference
Ichiyama Y, Matsumoto R, Obata S, Sawada O, Saishin Y, Kakinoki M, et al. Assessment of mouse VEGF neutralization by ranibizumab and aflibercept. PLoS ONE. 2022;17:e0278951 pubmed publisher
Wang J, Song W, Yang R, Li C, Wu T, Dong X, et al. Endothelial Wnts control mammary epithelial patterning via fibroblast signaling. Cell Rep. 2021;34:108897 pubmed publisher
Sounni N, Dehne K, van Kempen L, Egeblad M, Affara N, Cuevas I, et al. Stromal regulation of vessel stability by MMP14 and TGFbeta. Dis Model Mech. 2010;3:317-32 pubmed publisher
Lin H, Shabbir A, Molnar M, Yang J, Marion S, Canty J, et al. Adenoviral expression of vascular endothelial growth factor splice variants differentially regulate bone marrow-derived mesenchymal stem cells. J Cell Physiol. 2008;216:458-68 pubmed publisher
Horst A, Ito W, Dabelstein J, Schumacher U, Sander H, Turbide C, et al. Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo. J Clin Invest. 2006;116:1596-605 pubmed
Niida S, Kondo T, Hiratsuka S, Hayashi S, Amizuka N, Noda T, et al. VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. Proc Natl Acad Sci U S A. 2005;102:14016-21 pubmed
Qian D, Wang X, Kachhap S, Kato Y, Wei Y, Zhang L, et al. The histone deacetylase inhibitor NVP-LAQ824 inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584. Cancer Res. 2004;64:6626-34 pubmed
Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, et al. VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2. Invest Ophthalmol Vis Sci. 2004;45:368-74 pubmed
Banerjee K, Biswas P, Kim B, Lee S, Rouse B. CXCR2-/- mice show enhanced susceptibility to herpetic stromal keratitis: a role for IL-6-induced neovascularization. J Immunol. 2004;172:1237-45 pubmed

product information

master code :

494-VE

SKU :

494-VE-005

product name :

Recombinant Mouse VEGF 120 Protein

unit size :

5 ug (also 25 ug)

description :

The Recombinant Mouse VEGF 120 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse VEGF 120 Protein has been validated for the following applications: Bioactivity.

target :

VEGF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

14 kDa

gene symbol :

Vegfa

details of functionality :

Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 1-4 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAB22254

applications :

Bioactivity

source long :

E. coli -derived mouse VEGF protein Ala27-Arg146 (Gly117Glu & Glu118Arg)

source short :

E. coli

USD :

373 USD

alt names :

MVCD1, VAS, vascular endothelial growth factor A, Vascular permeability factor, Vasculotropin, VEGFA, VEGF-A, VEGFMGC70609, VPF, VPFvascular endothelial growth factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.