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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse VEGF 120 Protein
catalog :
494-VE-005
quantity :
5 ug (also 25 ug)
price :
365 USD
more info or order :
citations: 8
Reference
Ichiyama Y, Matsumoto R, Obata S, Sawada O, Saishin Y, Kakinoki M, et al. Assessment of mouse VEGF neutralization by ranibizumab and aflibercept. PLoS ONE. 2022;17:e0278951 pubmed publisher
Wang J, Song W, Yang R, Li C, Wu T, Dong X, et al. Endothelial Wnts control mammary epithelial patterning via fibroblast signaling. Cell Rep. 2021;34:108897 pubmed publisher
Lin H, Shabbir A, Molnar M, Yang J, Marion S, Canty J, et al. Adenoviral expression of vascular endothelial growth factor splice variants differentially regulate bone marrow-derived mesenchymal stem cells. J Cell Physiol. 2008;216:458-68 pubmed publisher
Horst A, Ito W, Dabelstein J, Schumacher U, Sander H, Turbide C, et al. Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo. J Clin Invest. 2006;116:1596-605 pubmed
Niida S, Kondo T, Hiratsuka S, Hayashi S, Amizuka N, Noda T, et al. VEGF receptor 1 signaling is essential for osteoclast development and bone marrow formation in colony-stimulating factor 1-deficient mice. Proc Natl Acad Sci U S A. 2005;102:14016-21 pubmed
Qian D, Wang X, Kachhap S, Kato Y, Wei Y, Zhang L, et al. The histone deacetylase inhibitor NVP-LAQ824 inhibits angiogenesis and has a greater antitumor effect in combination with the vascular endothelial growth factor receptor tyrosine kinase inhibitor PTK787/ZK222584. Cancer Res. 2004;64:6626-34 pubmed
Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, et al. VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2. Invest Ophthalmol Vis Sci. 2004;45:368-74 pubmed
Banerjee K, Biswas P, Kim B, Lee S, Rouse B. CXCR2-/- mice show enhanced susceptibility to herpetic stromal keratitis: a role for IL-6-induced neovascularization. J Immunol. 2004;172:1237-45 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
494-VE
SKU :
494-VE-005
product name :
Recombinant Mouse VEGF 120 Protein
Description :
The Recombinant Mouse VEGF 120 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse VEGF 120 Protein has been validated for the following applications: Bioactivity.
target :
VEGF
category :
Proteins and Enzymes
unit size :
5 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
theoretical molecular weight :
14 kDa
gene symbol :
Vegfa
details of functionality :
Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 1-4 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAB22254
applications :
Bioactivity
source :
E. coli-derived Recombinant Mouse VEGF 120 Protein
USD :
365 USD
alt names :
MVCD1, VAS, vascular endothelial growth factor A, Vascular permeability factor, Vasculotropin, VEGFA, VEGF-A, VEGFMGC70609, VPF, VPFvascular endothelial growth factor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.