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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse VEGF 164 Protein, CF
catalog :
493-MV-005/CF
quantity :
5 ug (also 25 ug)
price :
307 USD
more info or order :
citations: 77
Reference
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Ding X, Lucas T, Marcuzzi G, Pfister H, Eming S. Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8. Cancer Res. 2015;75:330-43 pubmed publisher
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Kawano N, Miyado K, Yoshii N, Kanai S, Saito H, Miyado M, et al. Absence of CD9 reduces endometrial VEGF secretion and impairs uterine repair after parturition. Sci Rep. 2014;4:4701 pubmed publisher
Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, et al. The docking protein FRS2? is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014;111:5514-9 pubmed publisher
Zhang H, Nieves J, Fraser S, Isern J, Douvaras P, Papatsenko D, et al. Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells. 2014;32:191-203 pubmed publisher
Hunter K, Palermo C, Kester J, Simpson K, Li J, Tang L, et al. Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors. Oncogene. 2014;33:1799-808 pubmed publisher
Raghuwanshi S, Smith N, Rivers E, Thomas A, Sutton N, Hu Y, et al. G protein-coupled receptor kinase 6 deficiency promotes angiogenesis, tumor progression, and metastasis. J Immunol. 2013;190:5329-36 pubmed publisher
Zhang G, Panigrahy D, Mahakian L, Yang J, Liu J, Stephen Lee K, et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2013;110:6530-5 pubmed publisher
Iwasaki T, Takeda Y, Maruyama K, Yokosaki Y, Tsujino K, Tetsumoto S, et al. Deletion of tetraspanin CD9 diminishes lymphangiogenesis in vivo and in vitro. J Biol Chem. 2013;288:2118-31 pubmed publisher
Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher
Caires K, de Avila J, Cupp A, McLean D. VEGFA family isoforms regulate spermatogonial stem cell homeostasis in vivo. Endocrinology. 2012;153:887-900 pubmed publisher
Cook B, Liu S, Evans T. Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment. Blood. 2011;117:6489-97 pubmed publisher
Lee H, Chauhan S, Kay E, Dana R. Flt-1 regulates vascular endothelial cell migration via a protein tyrosine kinase-7-dependent pathway. Blood. 2011;117:5762-71 pubmed publisher
Ruiz de Almodovar C, Coulon C, Salin P, Knevels E, Chounlamountri N, Poesen K, et al. Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1. J Neurosci. 2010;30:15052-66 pubmed publisher
Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid P, et al. The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice. J Clin Invest. 2009;119:2257-70 pubmed publisher
Irani Y, Brereton H, Tilton R, Coster D, Williams K. Production of scFv antibody fragments from a hybridoma with functional activity against human vascular endothelial growth factor. Hybridoma (Larchmt). 2009;28:205-9 pubmed publisher
Tian F, Liang P, Li L. Inhibition of endothelial progenitor cell differentiation by VEGI. Blood. 2009;113:5352-60 pubmed publisher
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Crawford Y, Kasman I, Yu L, ZHONG C, Wu X, Modrusan Z, et al. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell. 2009;15:21-34 pubmed publisher
Ponticelli S, Marasco D, Tarallo V, Albuquerque R, Mitola S, Takeda A, et al. Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1. J Biol Chem. 2008;283:34250-9 pubmed publisher
Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, et al. Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor. Exp Cell Res. 2008;314:3292-305 pubmed publisher
Noman A, Koide N, Khuda I, Dagvadorj J, Tumurkhuu G, Naiki Y, et al. Thalidomide inhibits epidermal growth factor-induced cell growth in mouse and human monocytic leukemia cells via Ras inactivation. Biochem Biophys Res Commun. 2008;374:683-7 pubmed publisher
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Yu L, Wu X, Cheng Z, Lee C, LeCouter J, Campa C, et al. Interaction between bevacizumab and murine VEGF-A: a reassessment. Invest Ophthalmol Vis Sci. 2008;49:522-7 pubmed publisher
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Zhang Z, Ramirez N, Yankeelov T, Li Z, Ford L, Qi Y, et al. alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner. Blood. 2008;111:1980-8 pubmed
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product information
brand :
R&D Systems
master code :
493-MV/CF
SKU :
493-MV-005/CF
product name :
Recombinant Mouse VEGF 164 Protein, CF
description :
The Recombinant Mouse VEGF 164 Protein, CF from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Mouse VEGF 164 Protein, CF has been validated for the following applications: Bioactivity.
target :
VEGF
category :
Proteins and Enzymes
sizes available :
5 ug (also 25 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
42 kDa, non-reducing conditions
theoretical molecular weight :
19.4 kDa (monomer)
gene symbol :
Vegfa
details of functionality :
Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. Conn, G. et al . (1990) Proc. Natl. Acad. Sci. USA 87 :1323. The ED50 for this effect is 0.8-4 ng/mL.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
AAA40547
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Mouse VEGF 164 Protein, CF
USD :
302
USD 2023 :
307 USD
alt names :
MVCD1, VAS, vascular endothelial growth factor A, Vascular permeability factor, Vasculotropin, VEGFA, VEGF-A, VEGFMGC70609, VPF, VPFvascular endothelial growth factor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.