Recombinant Human Carboxylesterase 1/CES1 Protein, CF | R&D Systems 4920-CE-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Carboxylesterase 1/CES1 Protein, CF

catalog :

4920-CE-010

quantity :

10 ug

price :

464 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Rees M, Brenan L, Do Carmo M, Duggan P, Bajrami B, Arciprete M, et al. Systematic identification of biomarker-driven drug combinations to overcome resistance. Nat Chem Biol. 2022;18:615-624 pubmed publisher
Li J, Liu S, Shi J, Zhu H. Activation of Tenofovir Alafenamide and Sofosbuvir in the Human Lung and Its Implications in the Development of Nucleoside/Nucleotide Prodrugs for Treating SARS-CoV-2 Pulmonary Infection. Pharmaceutics. 2021;13: pubmed publisher
Ajandouz E, Berdah S, Moutardier V, Bege T, Birnbaum D, Perrier J, et al. Hydrolytic Fate of 3/15-Acetyldeoxynivalenol in Humans: Specific Deacetylation by the Small Intestine and Liver Revealed Using in Vitro and ex Vivo Approaches. Toxins (Basel). 2016;8: pubmed publisher
Murakami E, Tolstykh T, Bao H, Niu C, Steuer H, Bao D, et al. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. J Biol Chem. 2010;285:34337-47 pubmed publisher

product information

brand :

R&D Systems

master code :

4920-CE

SKU :

4920-CE-010

product name :

Recombinant Human Carboxylesterase 1/CES1 Protein, CF

description :

The Recombinant Human Carboxylesterase 1/CES1 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Carboxylesterase 1/CES1 Protein, CF has been validated for the following applications: Enzyme Activity.

target :

Carboxylesterase 1/CES1

category :

Proteins and Enzymes

sizes available :

10 ug

buffer :

Supplied as a 0.2 µm filtered solution in Sodium Acetate and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

61 kDa, reducing conditions

theoretical molecular weight :

61 kDa

gene symbol :

CES1

details of functionality :

Measured by its ability to hydrolyze p-nitrophenylacetate. The specific activity is 6,000 pmol/min/µg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_001020365

applications :

Enzyme Activity

source :

NS0-derived Recombinant Human Carboxylesterase 1/CES1 Protein, CF

USD :

442

USD 2023 :

464 USD

alt names :

ACAT, acyl coenzyme A:cholesterol acyltransferase, Acyl-coenzyme A:cholesterol acyltransferase, Brain carboxylesterase hBr1, carboxylesterase 1, carboxylesterase 1 (monocyte/macrophage serine esterase 1), carboxylesterase 2 (liver), CEH, Ces-1, CES1, CES1A2, CES2EC 3.1.1.1, cholesteryl ester hydrolase, Cocaine carboxylesterase, EC 3.1.1, egasyn, HMSE1, HMSECES1A1, human monocyte/macrophage serine esterase 1, liver carboxylesterase 1, MGC117365, Monocyte/macrophage serine esterase, PCE-1, REH, Retinyl ester hydrolase, Serine esterase 1, Ses-1, SES1, SES1TGH, TGH, Triacylglycerol hydrolase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage