product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse CXCL9/MIG Protein
catalog :
492-MM-010
quantity :
10 ug (also 50 ug)
price :
318 USD
more info or order :
R&D Systems product webpage
citations: 10
Reference
Hashimoto M, Araki K, Cardenas M, Li P, Jadhav R, Kissick H, et al. PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program. Nature. 2022;610:173-181 pubmed publisher
Hasegawa T, Venkata Suresh V, Yahata Y, Nakano M, Suzuki S, Suzuki S, et al. Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation. Sci Rep. 2021;11:2613 pubmed publisher
Yano T, Ohira M, Nakano R, Tanaka Y, Ohdan H. Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice. PLoS ONE. 2017;12:e0186997 pubmed publisher
Allan E, Campden R, Ewanchuk B, Tailor P, Balce D, McKenna N, et al. A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis. J Neuroinflammation. 2017;14:103 pubmed publisher
Shinde P, Liu W, Menoret A, Luster A, Vella A. Optimal CD4 T cell priming after LPS-based adjuvanticity with CD134 costimulation relies on CXCL9 production. J Leukoc Biol. 2017;102:57-69 pubmed publisher
Krueger P, Narayanan S, Surette F, Brown M, Sung S, Hahn Y. Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells. J Leukoc Biol. 2017;101:329-338 pubmed publisher
Zychowska M, Rojewska E, Pilat D, Mika J. The role of some chemokines from the CXC subfamily in a mouse model of diabetic neuropathy. J Diabetes Res. 2015;2015:750182 pubmed publisher
Krauthausen M, Kummer M, Zimmermann J, Reyes Irisarri E, Terwel D, Bulic B, et al. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. J Clin Invest. 2015;125:365-78 pubmed publisher
Lacotte S, Decossas M, Le Coz C, Brun S, Muller S, Dumortier H. Early differentiated CD138(high) MHCII+ IgG+ plasma cells express CXCR3 and localize into inflamed kidneys of lupus mice. PLoS ONE. 2013;8:e58140 pubmed publisher
Liu C, Luo D, Reynolds B, Meher G, Katritzky A, Lu B, et al. Chemokine receptor CXCR3 promotes growth of glioma. Carcinogenesis. 2011;32:129-37 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
492-MM
SKU :
492-MM-010
product name :
Recombinant Mouse CXCL9/MIG Protein
Description :
The Recombinant Mouse CXCL9/MIG Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CXCL9/MIG Protein has been validated for the following applications: Bioactivity.
target :
CXCL9/MIG
category :
Proteins and Enzymes
unit size :
10 ug (also 50 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
theoretical molecular weight :
12 kDa
gene symbol :
Cxcl9
details of functionality :
Measured by its ability to chemoattract human peripheral blood lymphocytes (PBL) cultured in the presence of IL-2 for 21 days. The ED50 for this effect is 0.1-0.3 µg/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CXCR3. The ED50 for this effect is 0.1 - 0.5 µg/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P18340
applications :
Bioactivity
source :
E. coli-derived Recombinant Mouse CXCL9/MIG Protein
USD :
318 USD
alt names :
chemokine (C-X-C motif) ligand 9, CMK, crg-10, C-X-C motif chemokine 9, Gamma-interferon-induced monokine, Humig, MIG, MIGSmall-inducible cytokine B9, monokine induced by gamma interferon, SCYB9Monokine induced by interferon-gamma
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.