Recombinant Mouse CXCL9/MIG Protein | R&D Systems 492-MM-010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CXCL9/MIG Protein

catalog :

492-MM-010

quantity :

10 ug (also 50 ug)

price :

325 USD

citations: 11

Reference
Koya J, Tanigawa T, Mizuno K, Kim H, Ito Y, Yuasa M, et al. Modeling NK-cell lymphoma in mice reveals its cell-of-origin and microenvironmental changes and identifies therapeutic targets. Nat Commun. 2024;15:9106 pubmed publisher
Hashimoto M, Araki K, Cardenas M, Li P, Jadhav R, Kissick H, et al. PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program. Nature. 2022;610:173-181 pubmed publisher
Hasegawa T, Venkata Suresh V, Yahata Y, Nakano M, Suzuki S, Suzuki S, et al. Inhibition of the CXCL9-CXCR3 axis suppresses the progression of experimental apical periodontitis by blocking macrophage migration and activation. Sci Rep. 2021;11:2613 pubmed publisher
Yano T, Ohira M, Nakano R, Tanaka Y, Ohdan H. Hepatectomy leads to loss of TRAIL-expressing liver NK cells via downregulation of the CXCL9-CXCR3 axis in mice. PLoS ONE. 2017;12:e0186997 pubmed publisher
Allan E, Campden R, Ewanchuk B, Tailor P, Balce D, McKenna N, et al. A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis. J Neuroinflammation. 2017;14:103 pubmed publisher
Shinde P, Liu W, Menoret A, Luster A, Vella A. Optimal CD4 T cell priming after LPS-based adjuvanticity with CD134 costimulation relies on CXCL9 production. J Leukoc Biol. 2017;102:57-69 pubmed publisher
Krueger P, Narayanan S, Surette F, Brown M, Sung S, Hahn Y. Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells. J Leukoc Biol. 2017;101:329-338 pubmed publisher
Zychowska M, Rojewska E, Pilat D, Mika J. The role of some chemokines from the CXC subfamily in a mouse model of diabetic neuropathy. J Diabetes Res. 2015;2015:750182 pubmed publisher
Krauthausen M, Kummer M, Zimmermann J, Reyes Irisarri E, Terwel D, Bulic B, et al. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. J Clin Invest. 2015;125:365-78 pubmed publisher
Lacotte S, Decossas M, Le Coz C, Brun S, Muller S, Dumortier H. Early differentiated CD138(high) MHCII+ IgG+ plasma cells express CXCR3 and localize into inflamed kidneys of lupus mice. PLoS ONE. 2013;8:e58140 pubmed publisher
Liu C, Luo D, Reynolds B, Meher G, Katritzky A, Lu B, et al. Chemokine receptor CXCR3 promotes growth of glioma. Carcinogenesis. 2011;32:129-37 pubmed publisher

product information

master code :

492-MM

SKU :

492-MM-010

product name :

Recombinant Mouse CXCL9/MIG Protein

unit size :

10 ug (also 50 ug)

description :

The Recombinant Mouse CXCL9/MIG Protein from R&D Systems is derived from E. coli. The Recombinant Mouse CXCL9/MIG Protein has been validated for the following applications: Bioactivity.

target :

CXCL9/MIG

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

theoretical molecular weight :

12 kDa

gene symbol :

Cxcl9

details of functionality :

Measured by its ability to chemoattract human peripheral blood lymphocytes (PBL) cultured in the presence of IL-2 for 21ádays. The ED50 for this effect is 0.1-0.3á╡g/mL. Measured by its ability to chemoattract BaF3 mouse pro-B cells transfected with mouse CXCR3. The ED50 for this effect is 0.1 -á0.5á╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P18340

applications :

Bioactivity

source long :

E. coli -derived mouse CXCL9/MIG protein Thr22-Thr126

source short :

E. coli

USD :

325 USD

alt names :

chemokine (C-X-C motif) ligand 9, CMK, crg-10, C-X-C motif chemokine 9, Gamma-interferon-induced monokine, Humig, MIG, MIGSmall-inducible cytokine B9, monokine induced by gamma interferon, SCYB9Monokine induced by interferon-gamma

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.