product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Rat IL-1 RI Fc Chimera Protein, CF
catalog :
4895-MR-100
quantity :
100 ug
price :
456 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Yin J, Wang Y, Hu H, Li X, Xue M, Cheng W, et al. P2X7 receptor inhibition attenuated sympathetic nerve sprouting after myocardial infarction via the NLRP3/IL-1? pathway. J Cell Mol Med. 2017;21:2695-2710 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
4895-MR
SKU :
4895-MR-100
product name :
Recombinant Rat IL-1 RI Fc Chimera Protein, CF
description :
The Recombinant Rat IL-1 RI Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Rat IL-1 RI Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
IL-1 RI
unit size :
100 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Rat
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
85-100 kDa, reducing conditions
theoretical molecular weight :
64.3 kDa (monomer)
details of functionality :
Measured by its ability to inhibit IL-1 alpha -dependent proliferation in D10.G4.1 mouse helper T cells. Symons, J.A. et al . (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 272. Approximately 5-20 µg/mL of rrIL-1 RI/Fc Chimera will inhibit 50% of the biological response due to 15 pg/mL of rrIL-1a.
endotoxin note :
<0.01 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q02955
applications :
Bioactivity
product keywords :
4895-MR, rrIL-1 RI/Fc, rIL-1 RI, carrier-free, carrier free, 4895MR, IL-1RI, IL1RI, IL-1 R1, IL-1R1, IL 1 RI, Interleukin 1 Receptor I, IL1RI, Interleukin-1 R1, IL-1R 1 , cytokine, cytokines, sCD121a, sIL-1 RI, sIL-1RI, Th17
source :
NS0-derived Recombinant Rat IL-1 RI Fc Chimera Protein, CF
USD :
447
USD 2025 :
456 USD
alt names :
CD121 antigen-like family member A, CD121a, CD121a antigen, IL1R, IL1R1, IL1RI, IL-1RI, IL1RT1, IL-1RT1, IL-1RT-1, Interleukin 1 Receptor 1, interleukin 1 receptor, type I, interleukin receptor 1, interleukin-1 receptor type 1, p80
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.